66375-87-9

Basic information

• Product Name: N-[3-(4-pyridinyl)phenyl]acetamide
• Synonyms: N-[3-(4-pyridinyl)phenyl]acetamide
• CAS NO: 66375-87-9
• Molecular Weight: 212.251
• Mol File: 66375-87-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-[3-(4-pyridinyl)phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-(4-pyridinyl)phenyl]acetamide(66375-87-9)
• EPA Substance Registry System: N-[3-(4-pyridinyl)phenyl]acetamide(66375-87-9)

Safety Data

• Hazardous Substances Data: 66375-87-9(Hazardous Substances Data)

Upstream product

• 40034-44-4 3-(pyridin-4-yl)benzenamine 
• 94089-25-5 ethyl 5-oxo-2-[(4-pyridinyl)-carbonyl]hexanoate 
• 26377-17-3 ethyl 3-oxo-3-(4-pyridyl)propanoate 
• 63843-10-7 3-(4-Pyridinyl)-2-cyclohexen-1-one 
• 1570-45-2 isonicotinic acid ethylester 
• 108-24-7 acetic anhydride 
• 63843-22-1 3-(4-Pyridinyl)-2-cyclohexen-1-one oxime 

Downstream Products

• 40034-44-4 3-(pyridin-4-yl)benzenamine 

Relevant articles and documents

Process for preparing antibacterial compounds

4-(4-Halo-3-nitrophenyl)pyridines, useful as intermediates in the synthesis of antibacterial 1-alkyl-1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic acids, are obtained by nitrating 4-(4-halophenyl)pyridines. The 4-(4-halo-3-nitrohenyl)pyridines may be converted to the antibacterial agents by reducing them to 4-(3-aminophenyl)pyridines and then subjecting the amino compounds to suitable known reactions.

Cyclic alkylidenyl N-(lower-alkyl)-3-(pyridinyl)anilinomethylenemalonates

Cyclic alkylidenyl N-(lower-alkyl)-3-PY-anilinomethylenemalonates (I), where PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower-alkyl substituents, are prepared by reacting cyclic alkylidenyl (lower-alkoxy)methylenemalonate (II) with N-(lower-alkyl)-3-PY-aniline (III). Also, I is heated with polyphosphoric acid to produce 1-(lower-alkyl)-1,4-dihydro-4-oxo-7-PY-3-quinolinecarboxylic acid, known antibacterial agents. The N-(lower-alkyl)-3-PY-anilines are produced by reducing the corresponding N-(3-PY-phenyl)-(lower-alkanamides).