66427-26-7Relevant articles and documents
A practical entry to C18-constrained-E-ring analogues of methyllycaconitine (MLA): A concise new stereoselective approach to 8-oxa-decahydroisoquinolines accompanied by a simple microwaves-assisted synthesis of the succinimidobenzoate appendage of MLA
Simoni, Daniele,Rossi, Marcello,Rondanin, Riccardo,Baruchello, Riccardo,Grisolia, Giuseppina,Eleopra, Marco,Giovannini, Riccardo,Bozzoli, Andrea,Davalli, Silvia,Di Fabio, Romano,Donati, Daniele
, p. 759 - 762 (2005)
A Mannich-type intramolecular cyclization afforded access to a 8-oxa-decahydroisoquinoline heterocyclic system. Good stereoselectivity was observed. A promising microwave-assisted synthesis of the methylsuccinimidobenzoate moiety of methyllycaconitine has
Expedient synthesis of 3-substituted cycloalkanones via a Pd-catalyzed decarboxylative protonation protocol
Kim, Se Hee,Kim, Eun Sun,Kim, Taek Hyeon,Kim, Jae Nyoung
experimental part, p. 6256 - 6260 (2010/01/11)
We developed an efficient method for the introduction of -CH2EWG moiety at the β-position of 2-cycloalken-1-ones via a Pd-catalyzed decarboxylative protonation protocol.
Organotin perfluorooctanesulfonates as air-stable Lewis acid catalysts: Synthesis, characterization, and catalysis
An, De Lie,Peng, Zhihong,Orita, Akihiro,Kurita, Akinobu,Man-E, Sumiyo,Ohkubo, Kei,Li, Xingshu,Fukuzumi, Shunichi,Otera, Junzo
, p. 1642 - 1647 (2007/10/03)
The reactions of 1,3-dichloro-1,1,3,3-tetrabutyldistannoxane and di-alkyltin dihalides with silver perfluoro-octanesulfonate provided the corresponding sulfonates as hydrates. The number of water molecules (n) of hydration was dependent on the conditions. The distannoxane derivative was identified as n from 0.5 to 6, while in the hydrated mononuclear species and DMSO complexes n varied widely from 4 to 13. 119Sn NMR spectroscopy and conductivity measurements indicated the ionic dissociation of these compounds in solution. These compounds exhibited unusually high solubility in polar organic solvents. The ionic dissociation together with facile hydration probably causes the unusual solubility. The Lewis acidity of these compounds was found to be high among organotin derivatives on the basis of ESR spectra of Superoxide/ metal-ion complexes. In contrast to well-known organotin Inflates, these compounds suffered no hydrolysis upon storage in open air. The high catalytic activity of the distannoxane 1 was exemplified for various carboncarbon bond-forming reactions, such as Mukaiyama-aldol as well as -Michael reactions and allylation of aldehydes.
Indium-trichloride catalyzed Michael reaction of silyl enol ethers with α,β-unsaturated carbonyl compounds under neat condition
Loh, Teck-Peng,Wei, Lin-Li
, p. 7615 - 7624 (2007/10/03)
In the presence of a catalytic amount of indium (III) trichloride (InCl3) (20 mol%), ketene silyl enol ethers react quickly with α, β- unsaturated ketones and esters to afford the corresponding Michael adducts in moderate to good yields. Indium(III) trichloride can be recovered and reused without decrease in yields.
Unique Molecular Discrimination in Europium Complex-Catalyzed Reactions of Saturated and α,β-Unsaturated Ketones with Ketene Silyl Acetals
Hanyuda, Kiyoshi,Hirai, Kei-Ichi,Nakai, Takeshi
, p. 31 - 32 (2007/10/03)
The unique molecular discriminations are observed in the Eu(III)-catalyzed reactions of saturated ketones, α,β-enones, and α,β-ynones with ketene silyl acetals and discussed in terms of the discriminating ability of the Eu-catalyst at the complexation sta
Addition of Ketene Trimethylsilyl Acetals to α,β-Unsaturated Ketones: A New Strategy for Michael Addition of Ester Enolates
RajanBabu, T. V.
, p. 2083 - 2089 (2007/10/02)
Trialkylsilyl ketene acetals in the presence of tris(dimethylamino)sulfonium difluorotrimethylsiliconate generate very potent carbon nucleophiles formally equivalent to ester enolates.In sharp contrast to the commonly used lithium enolates, these acetals
