66534-94-9Relevant academic research and scientific papers
New Chiral Ligands designed for Palladium-catalysed Asymmetric Allylic Alkylation
Hayashi, Tamio,Kanehira, Koichi,Tsuchiya, Hiroyoshi,Kumada, Makoto
, p. 1162 - 1164 (1982)
New chiral phosphine ligands containing a chiral functional group remote from the phosphino-groups have been found to be effective in the palladium-catalysed reaction of allyl acetate with the enolate anion of 2-acetylcyclohexanone and give the allylated
Asymmetric hydrogenation with antibody-achiral rhodium complex
Yamaguchi, Hiroyasu,Hirano, Tohko,Kiminami, Hideaki,Taura, Daisuke,Harada, Akira
, p. 3571 - 3573 (2008/10/09)
An asymmetric hydrogenation of an amino acid precursor was catalyzed by the rhodium cyclooctadiene phosphine complex of a transition metal with immunoglobin. The hapten was covalently attached to a limpet hemocyanin (KLH) or bovine serum albumin (BSA) through activation of the carboxyl group in the hapten molecule using carbonyldiimidazole. The conjugates KLH-1 and BSA-1 were purified by size exclusion chromatography and used as an antigen to immunize mice and in enzyme linked immunosorbent assay (ELISA). The Rh complex was added to the aqueous solution of the monoclonal antibody under argon atmosphere at room temperature. It was found that the antibody IG8 could bind substrate than the hapten molecules, and the antibody IG8-Rh complex is stereoselective catalyst with substrate specificity through second sphere coordination.
Synthesis of Functional Chelating Diphosphines Containing the Bisamino Moiety and the Use of These Materials in the Preparation of Water-Soluble Diphosphine Complexes of Transition Metals
Nuzzo, Ralph G.,Haynie, Sharon L.,Wilson, Michael E.,Whitesides, George M.
, p. 2861 - 2867 (2007/10/02)
Acylation of bisamine provides a flexible synthesis of functionalized chelating diphosphines.This reaction offers a route to diphosphine complexes of transition metals having a wide range of structures and physical properties and especially to water-soluble complexes.The aqueous solubility of the free ligands and of the complexes prepared from them depend on the ligand, on the metal, and on other materials (especially surfactants) present in the solution.We describe typical preparations of ligands and outline the properties of their complexes with certain transition metals.
