666254-69-9

Upstream product

• 355836-10-1 2-methoxy-4-trifluoromethoxybenzeneboronic acid 
• 870689-48-8 5-bromo-N²-(1-ethyl-propyl)-6-methyl-pyrazine-2,3-diamine 
• 616-24-0 3-aminopentane 
• 827-99-6 3-(trifluoromethoxy)phenol 
• 870689-47-7 3,5-dibromo-N-(1-ethyl)propyl-6-methylpyrazine-2-amine 
• 205371-26-2 2-bromo-5-(trifluoromethyloxy)phenol 
• 848360-85-0 1-bromo-2-methoxy-4-(trifluoromethoxy)benzene 
• 355836-17-8 N-(1-ethyl)propyl-6-methylpyrazine-2-amine 
• 355836-15-6 6-chloro-[N-(1-ethyl)propyl]pyrazine-2-amine 

Downstream Products

• 870689-49-9 N-[3-(1-ethyl-propylamino)-6-(2-methoxy-4-trifluoromethoxy-phenyl)-5-methyl-pyrazin-2-yl]-acetamide 

Relevant academic research and scientific papers

5-Aryl-pyrazolo[4,3-d]pyrimidines, pyridines, and pyrazines and related compounds

5-aryl-Pyrazolo[4,3-d]pyrimidines, 6-aryl-Pyrazolo[3,4-d]pyrimidines and related compounds, as well as other chemically related compounds, that act as selective modulators of CRF 1 receptors are provided. These compounds are useful in the treatment of a n

IMIDAZOPYRAZINES, IMIDAZOPYRIDINES, ANS IMIDAZOPYRIMIDINES AS CRF1 RECEPTOR LIGANDS

Novel aryl substituted imidazopyrazines, imidazopyrimidines, and imidazopyridines are provided. Such compounds can act as selective modulators of CRF receptors. The 5-substituted-2-arylpyridine compounds provided herein are useful in the treatment of a nu

5-SUBSTITUTED-2-ARYLPYRAZINES AS MODULATORS OF CRF RECEPTORS

Novel 5-substituted-2-arylpyrazine compounds are provided. Such compounds can act as selective modulators of CRF receptors. The 5-substituted-2-arylpyrazine compounds provided herein are useful in the treatment of a number of CNS and peripheral disorders, particularly stress, anxiety, depression, cardiovascular disorders, and eating disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided. Compounds provided are also useful as probes for the localization of CRF receptors and as standards in assays for CRF receptor binding. Methods of using the compounds in receptor localization studies are given.