6667-60-3

Basic information

• Product Name: 3-Methylaspartic acid
• Synonyms: DL-THREO-BETA-METHYLASPARTIC ACID;DL-BETA-METHYLASPARTIC ACID;DL-ALPHA-METHYLASPARTIC ACID;BETA-METHYL-DL-ASPARTIC ACID;2-AMINO-2-METHYLSUCCINIC ACID;2-AMINO-3-METHYLSUCCINIC ACID;ALPHA-METHYL-DL-ASPARTIC ACID;DL-3-Methylaspartic acid
• CAS NO: 6667-60-3
• Molecular Formula: C₅H₉NO₄
• Molecular Weight: 147.13
• Product Categories: Chiral
• Mol File: 6667-60-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 270-276 °C
• Boiling Point: 259.2 °C at 760 mmHg
• Flash Point: 110.6 °C
• Appearance: white powder
• Density: 1.404 g/cm³
• Vapor Pressure: 0.00395mmHg at 25°C
• Refractive Index: 1.519
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.31±0.27(Predicted)
• CAS DataBase Reference: 3-Methylaspartic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methylaspartic acid(6667-60-3)
• EPA Substance Registry System: 3-Methylaspartic acid(6667-60-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 6667-60-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H9NO4/c1-2(4(7)8)3(6)5(9)10/h2-3H,6H2,1H3,(H,7,8)(H,9,10)

Upstream product

• 535-11-5 Ethyl 2-bromopropionate 
• 90877-70-6 ethyl 2-acetamido-2-cyanoacetate 
• 64-18-6 formic acid 
• 56512-51-7 2-amino-3-butenoic acid 
• 20268-80-8 diethyl 2-amino-3-methylsuccinate 
• 1068-90-2 2-acetylaminomalonic acid diethyl ester 
• 759-65-9 diethyl oxalpropionate 

Downstream Products

• 67513-61-5 (+/-)-threo-2-benzyloxycarbonylamino-3-methyl-succinic acid 
• 1492-24-6 L-2-aminobutyric acid 
• 127001-58-5 -Methylaspartat 
• 5380-36-9 (-)-threo-3-Methylaepfelsaeure 
• 5380-37-0 (2S,3S)-2-Hydroxy-3-methyl-succinic acid 
• 17335-93-2 DL-N-Benzyloxycarbonyl-3-methyl-Asp-dibenzylester 
• 17335-95-4 2-Benzyloxycarbonylamino-3-methyl-succinic acid 4-benzyl ester 
• 86535-06-0 (2R,3S)-threo-3-methylbutane-1,2,3-triol 4-benzyl ether 1-tosylate 
• 86562-36-9 (2R,3R)-threo-2-methylpentane-1,3-diol 3-THP ether 1-tosylate 
• 86535-10-6 (2S,3S)-threo-2-methylpentane-1,3-diol 3-THP ether 1-tosylate 
• 86535-18-4 2-methyl-3-pentanol (S)-(-)-MTPA ester 
• 86535-19-5 2-methyl-3-pentanol (R)-(+)-MTPA ester 
• 86535-17-3 (2R,3R)-threo-2-methylpentane-1,3-diol 1-tosylate 
• 86535-14-0 (2S,3S)-2-methyl-1-(4-methylbenzenesulfonyloxy)-3-pentanol 

Relevant articles and documents

Indium-mediated allylation and Reformatsky reaction on glyoxylic oximes under ultrasound irradiation

A novel and more convenient method for the indium-promoted allylation of glyoxylic oximes based on the use of ultrasonic waves is reported. A similar procedure was used to develop the first example reported in the literature of an indium-mediated Reformatsky reaction on oxime ethers.

FLAME-INDUCED CARBOXYLATION OF UNSATURATED AMINES IN AN AQUEOUS FORMIC ACID SOLUTION

When a hydrogen-oxygen flame was kept in contact with an aqueous formic acid solution of unsaturated amines, carboxylation onto a double bond took place.This reaction revealed to be initiated by addition of a hydrogen atom to the double bond followed by coupling of the resulted substrate radical with a carboxyl radical.