66685-49-2

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 93945-21-2 3-phenylquinoxaline-2-carboxaldehyde 
• 10130-23-1 2-methyl-3-phenylquinoxaline 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 123-11-5 4-methoxy-benzaldehyde 
• 7065-92-1 2-chloro-3-phenylquinoxaline 

Downstream Products

• 5021-43-2 2-phenylquinoxaline 
• 1023-17-2 4-methoxyphenyl benzyl ketone 

Relevant academic research and scientific papers

Discovery of 3-arylquinoxaline derivatives as potential anti-dengue virus agents

We designed and synthesized a series of novel 3-arylquinoxaline derivatives and evaluated their biological activities as potential dengue virus (DENV) replication inhibitors. Among them, [3-(4-methoxyphenyl)quinoxalin-2-yl](phenyl)methanol (19a), [6,7-dic

PIDA-mediated intramolecular oxidative C-N bond formation for the direct synthesis of quinoxalines from enaminones

A intramolecular oxidative C(sp2)-N bond formation mediated by hypervalent iodine(iii) to obtain quinoxalines from readily available N-(2-acetaminophenyl)enaminones was developed. A tandem process involving PIDA-mediated intramolecular condensation cyclization and a subsequent elimination was postulated, which was highly efficient and metal-free under mild conditions. Moreover, flexible structural modifications of quinoxalines bearing carbonyl groups are of interest for further transformations as building blocks in organic synthesis.

Synthesis of 2-aroylquinoxalines, 1-aroylphthalazines, and 4-aroylcinnolines; an aroylation method using arenecarbaldehydes catalyzed by azolium salt1

2-Aroylquinoxalines (5,6), 1-aroylphthalazines (10,11), and 4-aroylcinnolines (13) were synthesized by using arenecarbaldehydes (2) in the presence of an azolium salt (1) in moderate to good yields. 1,3-Dimethylimidazolium iodide (1a) and sodium sulfinate