93945-21-2

Upstream product

• 10130-23-1 2-methyl-3-phenylquinoxaline 
• 127-19-5 N,N-dimethyl acetamide 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 1420295-56-2 2-(dimethoxymethyl)-3-phenylquinoxaline 
• 67-56-1 methanol 
• 5021-43-2 2-phenylquinoxaline 

Downstream Products

• 111339-60-7 3-Phenylchinoxalin-2-carbaldehydtosylhydrazon 
• 1420295-56-2 2-(dimethoxymethyl)-3-phenylquinoxaline 
• 73377-99-8 2-Carboxamido-3-phenylquinoxaline 
• 5021-43-2 2-phenylquinoxaline 
• 66685-53-8 phenyl(3-phenylquinoxalin-2-yl)methanol 
• 111339-67-4 4-Phenyl-1,2,3-triazolo<1,5-a>chinoxalin 

Relevant academic research and scientific papers

Discovery of 3-arylquinoxaline derivatives as potential anti-dengue virus agents

We designed and synthesized a series of novel 3-arylquinoxaline derivatives and evaluated their biological activities as potential dengue virus (DENV) replication inhibitors. Among them, [3-(4-methoxyphenyl)quinoxalin-2-yl](phenyl)methanol (19a), [6,7-dic

Multifold bond cleavage and formation between meoh and quinoxalines (or benzothiazoles): Synthesis of carbaldehyde dimethyl acetals

A K2S2O8-mediated direct cross-coupling of quinoxalines (or benzothiazoles) with methanol leading to 2-quinoxalinyl (or 2-benzothiazolyl) carbaldehyde dimethyl acetals has been achieved. 2-Quinoxalinyl carbaldehyde dimethyl acetals were readily converted into 2-quinoxalinyl carbaldehydes in good to excellent yields under acidic conditions. Preliminary mechanistic studies suggest that the reaction proceeds via multifold bond cleavage and formation between methanol and N-heterocycles involving a dioxygen-participated radical process. This method allows for the synthesis of a variety of 2-quinoxalinyl (or 2-benzothiazolyl) carbaldehyde dimethyl acetals directly via cross-coupling of simple N-heterocyclic C-H bond and methanol under aldehyde-, acid-, and transition-metal-free conditions.

Highly efficient vinylaromatics generation via iron-catalyzed sp 3 C-H bond functionalization CDC reaction: A novel approach to preparing substituted benzo[α]phenazines

An iron-catalyzed benzylic vinylation was developed to transfer the carbon atom in the N,N-dimethyl moiety of N,N-dimethylacetamide (or N,N-dimethylformamide) to 2-methyl azaarenes to generate 2-vinyl azaarenes. The Royal Society of Chemistry.