6683-81-4

Usage

Uses

Used in Chemical Production:
2-TERT-BUTYL-4-NITROPHENOL is used as an intermediate in the production of various chemicals for its ability to facilitate the synthesis of rubber antioxidants, pesticides, and pharmaceuticals. Its chemical properties make it a key component in the creation of these products.
Used in Polymerization Inhibition:
2-TERT-BUTYL-4-NITROPHENOL is used as a polymerization inhibitor to prevent unwanted reactions in the polymerization process, ensuring the stability and quality of the final product.
Used in Stabilization of Oils and Fuels:
As a stabilizer for oils and fuels, 2-TERT-BUTYL-4-NITROPHENOL helps maintain the integrity and performance of these substances over time, preventing degradation and ensuring their safe and efficient use.
Safety and Environmental Considerations:
It is crucial to handle 2-TERT-BUTYL-4-NITROPHENOL with care due to its toxic nature. If swallowed, inhaled, or absorbed through the skin, it can pose serious health risks, including irritation to the eyes and skin. Moreover, it is harmful to aquatic life, necessitating proper handling and disposal in accordance with environmental regulations to minimize ecological impact.

Upstream product

• 6683-80-3 1-bromo-2-tert-butyl-4-nitro-benzene 
• 6683-78-9 N-(2-tert-butyl-phenyl)-4-methyl-benzenesulfonamide 
• 88-18-6 2-tert-Butylphenol 
• 100-02-7 4-nitro-phenol 
• 115-11-7 isobutene 
• 59255-98-0 2-(tert-butyl)-4-nitroaniline 
• 6683-79-0 1-tert-Butyl-5-nitro-2-tosylamino-benzol 

Downstream Products

• 158583-73-4 4-amino-2-t-butyl-6-(piperidin-1'-ylmethyl)phenol 
• 20294-59-1 2-bromo-6-tert-butyl-4-nitrophenol 
• 1132940-43-2 1-tert-butyl-3-iodo-2-methoxy-5-nitrobenzene 
• 1132937-45-1 N-(4-((3-(tert-butyl)-5-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-2-methoxyphenyl)ethynyl)phenyl)methanesulfonamide 
• 1132940-49-8 1-(3-tert-butyl-5-iodo-4-methoxyphenyl )dihydropyrimidine-2,4(1H,3H)-dione 
• 1132940-45-4 3-tert-butyl-5-iodo-4-methoxyaniline 
• 1132941-79-7 1-(3-(tert-butyl)-4-hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione 
• 35292-03-6 3-(tert-butyl)-4-methoxyaniline 
• 15353-20-5 2-tert.-Butyl-4-nitro-anisol 
• 1570188-89-4 (2-tert-butyl-4-nitro-6-{[(2'-dimethylaminoethyl)-methylamino]methyl}phenol-H)ZnSiOPh₃ 
• 1570188-74-7 2-tert-butyl-4-nitro-6-{[(2'-dimethylaminoethyl)methylamino]methyl}phenol 
• 32750-26-8 2-(tert-butyl)-6-iodo-4-nitrophenol 
• 158583-68-7 2-t-butyl-4-nitro-6-(piperidin-1'-ylmethyl)phenol 
• 1420-07-1 2-tert-butyl-4,6-dinitrophenol 

Relevant academic research and scientific papers

Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral Bioavailability

ABT-072 is a non-nucleoside HCV NS5B polymerase inhibitor that was discovered as part of a program to identify new direct-acting antivirals (DAAs) for the treatment of HCV infection. This compound was identified during a medicinal chemistry effort to impr

Synthesis of differently substituted tacn-based ligands: Towards the control of solubility and electronic and steric properties of uranium coordination complexes

Starting from phenols R1,R2ArOH (5) and the anisole derivative 3,5-di-tert-butyl-2-methoxybenzyl bromide (13), a series of new tacn-based ligands (R1,R2ArOR3)3tacn (2) have been synthesized with substituents of

URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C

Present application relates to the compounds of formula I useful to treat hepatitis C (HCV) infections. In the structure of the disclosed compounds is the uracil or thymine derivative linked via a phenylene into either fused 2-ring cyclic system (R6) or alternatively via additional two-atom linker (L) to a 5-6 membered monocycle (R6). Application further discloses polymorphs and pseudopolymorphs of two specific compounds: N-(6(3-t-butyl-5-(2>4-dioxo-3,4-dihydropyrimidin-1 (2H)- y!)2-methoxy-phenyl)naphthalen-2-yl)methanesulfonamide and (E)-N-(4(3-t- butyl-5-(2,4-dioxo-3)4-dihydropyrimidin-1 (2H)-yl)2-methoxy-styryl- phenyl)methanesulfonamide.

ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF

This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.

N-PHENYL-DIOXO-HYDROPYRIMIDINES USEFUL AS HEPATITIS C VIRUS (HCV) INHIBITORS

This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such interm