66831-21-8Relevant articles and documents
Structure-activity study of the nociceptin(1-13)-NH2 N-terminal tetrapeptide and discovery of a nociceptin receptor antagonist
Calo', Girolamo,Guerrini, Remo,Bigoni, Raffaella,Rizzi, Anna,Bianchi, Clementina,Regoli, Domenico,Salvadori, Severo
, p. 3360 - 3366 (1998)
In the present study, the minimal fragment sequence required to fully activate the nociceptin (NC) receptor, namely NC(1-13)-NH2, was used as template for the design of a series of new compounds. Changes were made in the N-terminal tetrapeptide
Methionine5 -enkephalin sulfoxides and sulfones
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, (2008/06/13)
Methionine 5 -enkephalin sulfoxides and sulfones having agonist activity at opiate receptors are disclosed herein. These sulfoxides and sulfones are useful as analgesics, non-addicting narcotic antagonists and anti-diarrheal agents.