668980-22-1

Basic information

• Product Name: Pyrido[2,3-d]pyrimidin-4-amine, 2-chloro-N-[(2,4-dichlorophenyl)methyl]-
• CAS NO: 668980-22-1
• Molecular Formula: C14H9Cl3N4
• Molecular Weight: 339.611
• Mol File: 668980-22-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Pyrido[2,3-d]pyrimidin-4-amine, 2-chloro-N-[(2,4-dichlorophenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrido[2,3-d]pyrimidin-4-amine, 2-chloro-N-[(2,4-dichlorophenyl)methyl]-(668980-22-1)
• EPA Substance Registry System: Pyrido[2,3-d]pyrimidin-4-amine, 2-chloro-N-[(2,4-dichlorophenyl)methyl]-(668980-22-1)

Safety Data

• Hazardous Substances Data: 668980-22-1(Hazardous Substances Data)

Upstream product

• 126728-20-9 2,4-dichloropyrido[2,3-d]pyrimidine 
• 95-00-1 2,4-dichloro-benzenemethanamine 
• 21038-66-4 2,4-dihydroxy-pyrido[2,3-d]pyrimidine 
• 5345-47-1 2-aminopyridin-3-carboxylic acid 

Downstream Products

• 668980-23-2 N-(2,4-dichlorobenzyl)-2-(piperazin-1-yl)pyrido[2,3-d]pyrimidin-4-amine 
• 936025-56-8 2-{4-[4-(2,4-dichloro-benzylamino)-pyrido[2,3-d]pyrimidin-2-yl]-piperazine-1-carbonyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 936025-59-1 2-{4-[4-(2,4-dichloro-benzylamino)-pyrido[2,3-d]pyrimidin-2-yl]-piperazine-1-carbonyl}-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 936025-42-2 4-[4-(2,4-dichloro-benzylamino)-pyrido[2,3-d]pyrimidin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

PIPERAZINYL PYRIMIDINE DERIVATIVES, PREPARATION METHOD AND USE THEREOF

Provided are piperazinyl pyrimidine derivatives of formula I having CCR4 antagonism, and the preparation method, pharmaceutical composition and use thereof in the preparation of a medicament. The medicament is useful for the treatment and preve

Design and synthesis of a series of pyrido[2,3-d]pyrimidine derivatives as CCR4 antagonists

A series of pyrido[2,3-d]pyrimidine derivatives were designed and synthesized based on known CC chemokine receptor 4 (CCR4) antagonists. The activities of all the newly synthesized compounds were evaluated using a chemotaxis inhibition assay. Compound 6b

Antagonists of chemokine receptors

Compounds are provided which are antagonists of chemokine receptor activity. The compounds thereof have the structure including enantiomers, diastereomers, tautomers, pharmaceutically acceptable salts and solvates thereof wherein: A, B, D, E, X and Y are