67019-56-1

Upstream product

• 16807-60-6 3-methoxycyclohex-2-en-1-one 
• 504-02-9 1,3-cylohexanedione 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 117360-96-0 3-<(1-methylpropyl)oxy>-2-cyclohexen-1-one 
• 1206544-10-6 4′-methoxy-3,4-dihydro-[1,1′-biphenyl]-1(2H)-ol 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 930-68-7 cyclohexenone 
• 17159-98-7 3-(4-methoxyphenyl)-2-cyclohexen-1-one 

Downstream Products

• 67019-52-7 2-(4′-methoxy-4-oxo-1,2,3,4-tetrahydro-[1,1′-biphenyl]-1-yl)-N,N-dimethylacetamide 
• 34603-52-6 1-[2-(dimethylamino)ethyl]-4'-methoxy-2,3-dihydro-[1,1′-biphenyl]-4(1H)-one 
• 1497432-49-1 (R)-4'-methoxy-3,4,5,6-tetrahydro-[1,1'-biphenyl]-3-ol 
• 1497432-44-6 (R)-3-(4-methoxyphenyl)cyclohex-2-enyl acetate 
• 17159-98-7 3-(4-methoxyphenyl)-2-cyclohexen-1-one 
• 1497432-32-2 3-(4-methoxyphenyl)cyclohex-2-enyl acetate 
• 1497432-43-5 C₂₆H₃₀O₃ 
• 67019-53-8 1-(2-(dimethylamino)ethyl)-4′-methoxy-1,2,3,4-tetrahydro-[1,1′-biphenyl]-4-ol 
• 34603-53-7 1-[2-(dimethylamino)ethyl]-4'-hydroxy-2,3-dihydro-[1,1'-biphenyl]-4(1H)-one 
• 67019-55-0 2-(4'-methoxy-1,2,3,4-tetrahydro-[1,1'-biphenyl]-1-yl)-N,N-dimethylacetamide 
• 135068-48-3 4′,5-dimethoxy-2,3,4,5-tetrahydro-1,1′-biphenyl 

Relevant academic research and scientific papers

Arene Trifunctionalization with Highly Fused Ring Systems through a Domino Aryne Nucleophilic and Diels–Alder Cascade

A convenient and efficient domino aryne process was developed under transition-metal-free conditions to generate a range of tetra- and pentacyclic ring systems. This transformation was realized via a 1,2-benzdiyne through a nucleophilic and Diels–Alder reaction cascade using styrene as the diene moiety. Three new chemical bonds, namely one C?N and two C?C bonds, and two benzofused rings could be constructed concomitantly, which was made possible by distinct chemoselective control at both the 1,2-aryne and 2,3-aryne stages. Moreover, in-depth studies were carried out on the domino aryne precursors and controlling the diastereoselectivity.

Concise Total Syntheses of (±)-Joubertiamine, (±)- O -Methyljoubertiamine, (±)-3′-Methoxy-4′- O -methyljoubertiamine, (±)-Mesembrane, and (±)-Crinane

A method to access cis-3a-aryloctahydroindole alkaloids has been developed through a key strategy involving Eschenmoser-Claisen rearrangement of allylalcohol. This approach gives us an opportunity to access the all-carbon quaternary center required for ci

Palladium-catalyzed oxidative rearrangement of tertiary allylic alcohols to enones with oxygen in aqueous solvent

A one-pot procedure for Pd(TFA)2-catalyzed 1,3-isomerization of tertiary allylic alcohols to secondary allylic alcohols followed by a Pd(TFA)2/neocuproine-catalyzed oxidative reaction to β-disubstituted-α,β-unsaturated kenones was developed. (Chemical Equation Presented).

Enzyme- and ruthenium-catalyzed dynamic kinetic resolution of functionalized cyclic allylic alcohols

Enantioselective synthesis of functionalized cyclic allylic alcohols via dynamic kinetic resolution has been developed. Cyclopentadienylruthenium catalysts were used for the racemization, and lipase PS-IM or CALB was employed for the resolution. By optimization of the reaction conditions the formation of the enone byproduct was minimized, making it possible to prepare a range of optically active functionalized allylic alcohols in good yields and high ee's.