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CAS

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67073-46-5

1-(2-benzylidenehydrazinyl)phthalazine, also known as BP or Phthalazine, is a chemical compound with the molecular formula C16H14N4. It is an organic compound containing a phthalazine ring system and a benzylidenehydrazinyl group attached at the 1-position. BP is recognized for its strong antitumor and antiviral activity, making it a significant building block in the development of potential therapeutic agents. It also holds promise for applications in the treatment of respiratory and cardiovascular diseases, showcasing its importance in medicinal chemistry and drug discovery.

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  • 67073-46-5 Structure

  • Basic information

    1. Product Name: 1-(2-benzylidenehydrazinyl)phthalazine
    2. Synonyms: 1-(2-benzylidenehydrazinyl)phthalazine
    3. CAS NO:67073-46-5
    4. Molecular Formula: C15H12N4
    5. Molecular Weight: 248.28258
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 67073-46-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(2-benzylidenehydrazinyl)phthalazine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(2-benzylidenehydrazinyl)phthalazine(67073-46-5)
    11. EPA Substance Registry System: 1-(2-benzylidenehydrazinyl)phthalazine(67073-46-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 67073-46-5(Hazardous Substances Data)

67073-46-5 Usage

Uses

Used in Pharmaceutical Industry:
1-(2-benzylidenehydrazinyl)phthalazine is used as a synthetic intermediate for the development of various biologically active compounds and pharmaceutical drugs. Its unique structure and properties contribute to the creation of novel therapeutic agents.
Used in Antitumor Applications:
In the field of oncology, 1-(2-benzylidenehydrazinyl)phthalazine is utilized as an antitumor agent. Its strong antitumor activity makes it a valuable compound in the fight against cancer, potentially leading to the development of new cancer treatments.
Used in Antiviral Applications:
BP also serves as an antiviral agent, with potential applications in the development of treatments for various viral infections. Its ability to combat viruses makes it a crucial component in the ongoing battle against emerging and existing viral threats.
Used in Respiratory and Cardiovascular Disease Treatment:
1-(2-benzylidenehydrazinyl)phthalazine has been studied for its potential use in the treatment of respiratory and cardiovascular diseases. Its involvement in these therapeutic areas highlights its versatility and the broad scope of its potential applications in medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 67073-46-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,0,7 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 67073-46:
(7*6)+(6*7)+(5*0)+(4*7)+(3*3)+(2*4)+(1*6)=135
135 % 10 = 5
So 67073-46-5 is a valid CAS Registry Number.

67073-46-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[(E)-benzylideneamino]phthalazin-1-amine

1.2 Other means of identification

Product number -
Other names Benzaldehyd-phthalazin-1-ylhydrazon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:67073-46-5 SDS

67073-46-5Relevant articles and documents

s-Triazolo[3,4-a]phthalazines from 1-phthalazinylhydrazones by thianthrene cation radical perchlorate

Park, Koon Ha,Jun, Kun,Shin, Seung Rim,Oh, Sea Wha

, p. 583 - 589 (2007/10/03)

1-Phthalazinylhydrazones 4 gave s-triazolo[3,4-a]phthalazines 5 in 94- 98% yields by thianthrene cation radical perchlorate (Th+(·)ClO4-).

Synthesis and Benzodiazepine Binding Activity of a Series of Novel Triazoloquinazolin-5(6H)-ones

Francis, John E.,Cash, William D.,Barbaz, Beverly S.,Bernard, Patrick S.,Lovell, Richard A.,et al.

, p. 281 - 290 (2007/10/02)

Investigation of tricyclic heterocycles related to the 2-arylpyrazoloquinolin-3(5H)-ones, structures with high affinity for the benzodiazepine (BZ) receptor, led to the synthesis of 2-phenyl-triazoloquinazolin-5(6H)-one, a compound wi

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