70591-70-7Relevant academic research and scientific papers
Potential antibacterial agents: Part VI- synthesis and structure elucidation of Schiff bases derived from hydralazine
Sultana, Naheed,Sarfaraz, Tahira B.,Nelofar, Aisha,Hussain, Shaheen A.
, p. 169 - 172 (2008/09/21)
Synthesis of hydrazones (Schiff bases) of an antihypertensive drug, hydralazine was carried out. The study afforded the hitherto unreported l-[4-chlorobenzylidene]-hydrazinophthalazine (III-a), l-[benzylidene]- hydrazinophthalazine (III-b), l-[4-nitrobenzylidene]-hydrazinophthalazine (III-c), l-[2-nitrobenzylidene]-hydrazinophthalazine (III-d), 3-[4-chlorophenyl]-s-triazolo [3-4-a] phthalazine (IV-a) and 3-phenyl-s-triazolo [3-4-a] phthalazine (IV-b). The structures of these compounds were established using spectroscopic techniques i.e. IR, UV, 1HNMR, EIMS, FD and HRMS. Antibacterial activity of the drugs was evaluated.
s-Triazolo[3,4-a]phthalazines from 1-phthalazinylhydrazones by thianthrene cation radical perchlorate
Park, Koon Ha,Jun, Kun,Shin, Seung Rim,Oh, Sea Wha
, p. 583 - 589 (2007/10/03)
1-Phthalazinylhydrazones 4 gave s-triazolo[3,4-a]phthalazines 5 in 94- 98% yields by thianthrene cation radical perchlorate (Th+(·)ClO4-).
Hypervalent iodine mediated synthesis of 3-substituted-s-triazolo phthalazines
Prakash, Om,Batra, Hitesh,Sharma, Viyay,Singh, Shiv P.
, p. 583 - 584 (2007/10/03)
Phthalazine hydrazones 1a-g on oxidation with iodobenene diacetate (IBD) in dichloromethane yield exclusively the 3-substituted-s-triazolophthalazines 2a-g.
Synthesis and Benzodiazepine Binding Activity of a Series of Novel Triazoloquinazolin-5(6H)-ones
Francis, John E.,Cash, William D.,Barbaz, Beverly S.,Bernard, Patrick S.,Lovell, Richard A.,et al.
, p. 281 - 290 (2007/10/02)
Investigation of tricyclic heterocycles related to the 2-arylpyrazoloquinolin-3(5H)-ones, structures with high affinity for the benzodiazepine (BZ) receptor, led to the synthesis of 2-phenyl-triazoloquinazolin-5(6H)-one, a compound wi
