6721-03-5

Basic information

• Product Name: N,N'-methanediylidenebis(1-phenylmethanamine)
• Synonyms: N,N'-methanediylidenebis(1-phenylmethanamine)
• CAS NO: 6721-03-5
• Molecular Weight: 222.29
• Mol File: 6721-03-5.mol

Chemical Properties

• CAS DataBase Reference: N,N'-methanediylidenebis(1-phenylmethanamine)(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-methanediylidenebis(1-phenylmethanamine)(6721-03-5)
• EPA Substance Registry System: N,N'-methanediylidenebis(1-phenylmethanamine)(6721-03-5)

Safety Data

• Hazardous Substances Data: 6721-03-5(Hazardous Substances Data)

Upstream product

• 1424-14-2 dibenzyl thiourea 
• 3173-56-6 benzyl isothiocyanate 
• 71-43-2 benzene 
• 1466-67-7 1,3-dibenzylurea 
• 100-39-0 benzyl bromide 
• 88333-03-3 Benzyl isocyanide 
• 622-79-7 benzyl azide 
• 622-78-6 Benzyl isothiocyanate 
• 100-46-9 benzylamine 

Downstream Products

• 138416-31-6 N-benzoyl-N,N'-dibenzyl-urea 
• 119415-54-2 O^5'-[(N,N'-Dibenzyl-ureido)-hydroxy-phosphoryl]-riboflavin 
• 51138-82-0 benzyl-(7-chloro-1,1-dioxo-1,2(4)-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-yl)-amine 
• 54999-92-7 N-(2,4-dibenzyl-3-benzylimino-[1,2,4]thiadiazolidin-5-ylidene)-toluene-4-sulfonamide 
• 38825-59-1 3-benzyl-2-benzylimino-1,1-dioxo-1λ⁶-thiazolidin-4-one 
• 52917-30-3 N,N'-Dibenzyl-N-aethoxycarbonylharnstoff 
• 1466-67-7 1,3-dibenzylurea 
• 87763-36-8 N,N'-dibenzyl-N-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinanyl)-thiourea 
• 64643-59-0 C₂₃H₃₃N₂O₃PS 
• 70206-07-4 N-(diphenylphosphoryl)-N,N'-dibenzylurea 
• 81017-67-6 C₂₅H₃₇N₂O₂PS₂ 
• 64643-58-9 C₂₁H₂₉N₂O₃PSe 
• 64674-21-1 C₂₅H₃₇N₂O₃PSe 
• 108762-52-3 C₂₆H₂₅N₂O₃PS 

Relevant articles and documents

Gram Scalable Method to Synthesize Biscarbodiimides and Asymmetric Monocarbodiimides: A Platform to Access an Array of Phosphaguanidines, Amidines, and Guanidines

A mild, broadly functional group tolerant methodology has been developed to access a variety of mono- and bis-carbodiimides in good yield and high purity on multigram scale. Direct addition into these versatile motifs facilitated the rapid synthesis of a library of novel amidinines, guanidines, and phosphaguandines.

Pos [...] 4 group metal olefin polymerization catalyst

Embodiments are directed to phosphaguanidine metal complexes of formula I and using those complexes in α-olefin polymerization systems.

Rhenium-Catalyzed Synthesis of 1,3-Diiminoisoindolines via Insertion of Carbodiimides into a C-H Bond of Aromatic and Heteroaromatic Imidates

The rhenium-catalyzed synthesis of 1,3-diiminoisoindolines and their related compounds from aromatic or heteroaromatic imidates and carbodiimides are reported via C-H bond activation. This reaction is the first example of a transition-metal-catalyzed inse

Palladium-catalyzed cross-coupling reaction of azides with isocyanides

An efficient palladium-catalyzed cross-coupling reaction of azides with isocyanides is developed, providing a general synthetic route to unsymmetric carbodiimides with excellent yields. This method shows a broad substrate scope, including not only aryl azides, but also unactivated benzyl and alkyl azides. Furthermore, from readily available substrates, Pd-catalyzed coupling with a tandem amine insertion cascade to obtain unsymmetric trisubstituted guanidines has been achieved in a one-pot fashion.

Pushing back the limits of hydrosilylation: Unprecedented catalytic reduction of organic ureas to formamidines

Pushing back the limits: A novel catalytic transformation has been designed to prepare formamidine derivatives by reduction of substituted ureas with hydrosilanes. Simple iron catalysts based on commercially available iron salts and phosphine ligands prov

Regioselective multicomponent sequential synthesis of hydantoins

The development of new practical and green methods for the synthesis of small heterocycles is an attractive area of research due to the well-known potential of heterocyclic small molecule scaffolds in the drug discovery process. Herein we report a one-pot, three-component sequential procedure for the synthesis of diversely 1,3,5- and 1,3,5,5-substituted hydantoins, in high yields and very mild conditions, using readily accessible starting materials such as azides, iso(thio)cyanates and substituted α-halo-acetic carboxylic acids. This methodology is especially convenient for the synthesis of spiro-hydantoins, which are particularly interesting bioactive compounds in medicinal chemistry. The Royal Society of Chemistry 2012.

O-Iodoxybenzoic acid mediated oxidative desulfurization of 1,3-disubstituted thioureas to carbodiimides

An efficient and mild oxidative desulfurization procedure using o-iodoxybenzoic acid has been developed for the synthesis of carbodiimides starting from easily synthesizable 1,3-disubstituted thioureas.

ARYLMETHYL ISOCYANATES

Chloromethyl isocyanate reacts readily with aromatic hydrocarbons in the presence of anhydrous ferric chloride or other catalysts of the Friedel-Crafts reaction with the formation of arylmethyl isocyanates.The latter add alcohols and amines readily, being converted into the corresponding substituted urethanes and ureas.When heated in the presence of catalytic amounts of 1,3-dimethylphosphol-3-ene they give substituted carbodiimides.

Oxidation of Mixtures of Thioureas: Part VII - Formation of 4-Alkyl-5-alkylimino-3-amino-4,5-dihydro-1,2,4-thiadiazoles

Oxidation of acidic ethanolic solutions of binary mixtures of 1,3-diethyl, 1,3-di-n-propyl, 1,3-diisopropyl, 1,3-di-n-butyl, 1,3-dibenzyl, 1-benzyl-3-methyl, 1-benzyl-3-ethyl, 1-benzyl-3-n-propyl, 1-benzyl-3-n-butyl, 1-n-butyl-3-n-propyl-thioureas with thiourea has been found to yield the related 4-alkyl-5-alkylimino-3-amino-4,5-dihydro-1,2,4-thiadiazoles (3).The mechanism of formation of these thiadiazoles has been discussed.One of the intermediates, viz. bis(formamidino)sulphide salt has been alternatively prepared and its further reactions studied.