67257-68-5

Basic information

• Product Name: Ethanone, 1-(3,4-dimethoxyphenyl)-2-(1-methyl-2-pyrrolidinyl)-
• CAS NO: 67257-68-5
• Molecular Formula: C15H21NO3
• Molecular Weight: 263.337
• Mol File: 67257-68-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(3,4-dimethoxyphenyl)-2-(1-methyl-2-pyrrolidinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(3,4-dimethoxyphenyl)-2-(1-methyl-2-pyrrolidinyl)-(67257-68-5)
• EPA Substance Registry System: Ethanone, 1-(3,4-dimethoxyphenyl)-2-(1-methyl-2-pyrrolidinyl)-(67257-68-5)

Safety Data

• Hazardous Substances Data: 67257-68-5(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(3,4-dimethoxyphenyl)-2-(1-methyl-2-pyrrolidinyl)-, also known as 3,4-methylenedioxyethcathinone, is a synthetic cathinone derivative that acts as a psychoactive stimulant. It is a substituted methcathinone that is structurally related to ephedrine and cathinone. This chemical is often used as a recreational drug and has been associated with a range of adverse health effects, including increased heart rate, elevated blood pressure, and potential for addiction. It is also important to note that the use and possession of this substance is illegal in many countries.

Upstream product

• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 68078-09-1 N-methylproline 
• 10441-57-3 1-methyl-pyrrolidine-2-thione 
• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 114883-82-8 N-methyl-D-proline methyl ester 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 94882-50-5 1-methyl-2-veratroylmethylene-pyrrolidine 
• 4687-37-0 ethyl 3,4-dimethoxybenzoylacetate 
• 20297-37-4 1-methyl-2-pyrrolidinecarbonitrile 
• 186581-53-3 diazomethane 
• 126262-24-6 (-)-phyllostone 

Relevant articles and documents

Biomimetic Approach toward the Total Synthesis of rac-2-(Acylmethylene)pyrrolidine Alkaloids

2-(Acylmethylene)pyrrolidine derivatives were synthesized via intermolecular decarbonylative Mannich reaction from various methyl ketones and 1-alkyl-1-pyrroliniums, generated in situ from 1-alkylprolines. This approach mimics the biosynthetic pathway and provides a direct access to a series of 2-(acylmethylene)pyrrolidine alkaloids, including hygrine, N-methylruspolinone, dehydrodarlinine, and ruspolinone.

THE APPLICATION OF THE SULPHIDE CONTRACTION TO THE SYNTHESIS OF SOME SIMPLE PYRROLIDINE ALKALOIDS

The alkaloids (+/-)-hygrine, (+/-)-dehydrodarlinine, (+/-)-dehydrodarlingianine, and (+/-)-N-methylruspolinone have been synthesised by selective reduction of vinylogous amides formed by sulphide contraction of the salts prepared by reaction of N-methyl-2