67263-05-2

Upstream product

• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 3839-31-4 dimethyl(phenyl)silyllithium 
• 4192-77-2 ethyl cinnamate 
• 768-33-2 phenyldimethylsilyl chloride 
• 91076-08-3 bis(dimethylphenylsilyl)zinc 
• 185990-03-8 dimethylphenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane 
• 889129-99-1 ethyl (Z)-3-(dimethyl(phenyl)silyl)-3-phenyl-2-propenoate 
• 4610-69-9 (Z)-ethyl cinnamate 
• 98-88-4 benzoyl chloride 
• 17909-51-2 (dimethyl(phenyl)silyl)(phenyl)methanone 
• 1468-28-6 4-benzoylmorpholine 

Downstream Products

• 67263-06-3 3-(dimethyl(phenyl)silyl)-3-phenylpropanal 
• 212180-73-9 3-(Dimethyl-phenyl-silanyl)-3-phenyl-propionic acid hydrazide 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 144452-46-0 3-(Dimethyl-phenyl-silanyl)-3-phenyl-propionyl chloride 
• 212180-90-0 3-(Dimethyl-phenyl-silanyl)-3-phenyl-propionyl azide 
• 212180-75-1 4-(Dimethyl-phenyl-silanyl)-4-phenyl-butyric acid hydrazide 
• 212180-93-3 4-(Dimethyl-phenyl-silanyl)-4-phenyl-butyryl azide 
• 5381-86-2 (1R,3S)-1,3-diphenylpropane-1,3-diol 
• 5381-86-2 (+/-)-(RS,RS)-1,3-diphenyl-1,3-propanediol 
• 191917-31-4 2-[3-(Dimethyl-phenyl-silanyl)-3-phenyl-propylidene]-malonic acid dimethyl ester 
• 191916-86-6 (Z)-5-(Dimethyl-phenyl-silanyl)-5-phenyl-pent-2-enoic acid methyl ester 

Relevant academic research and scientific papers

Method for preparing organic silicon compound by catalyzing chitosan-loaded copper film material

The invention discloses a method for preparing an organosilicon compound by catalyzing a chitosan-loaded copper film material, which comprises the following steps: adding water into the chitosan-loaded copper film material, and uniformly stirring at room

Basic Copper Carbonate-Catalyzed Silyl Conjugate Additions to α,β-Unsaturated Carbonyls in Water

We report here the silylation of α,β-unsaturated acceptors in water at room temperature using a copper catalyst. A broad substrate scope, including chalcone derivatives, esters, nitrile, and dienones, has been explored. In all cases, the reaction proceede

Method used for preparing organic silicon compounds and beta-hydroxyl compounds via bivalent copper ion catalysis

The invention relates to a method used for preparing organic silicon compounds and beta-hydroxyl compounds via bivalent copper ion catalysis. According to the method, a bivalent copper salt is taken as a catalyst, a pyridyl compound is taken as a ligand, bis(pinacolato)diboron dimethylsilane reagent is taken as a silicon reagent, and pure water is taken as a solvent; silicone additive reaction of alpha, beta-unsaturated carbonyl compounds with different substituent groups is carried out so as to obtain the organic silicon compounds; potassium bromide and peracetic acid are added directly without separation and purification of the organic silicon compounds, and the beta-hydroxyl compounds are obtained via oxidation. The advantages of the method are that: the method is simple and convenient; the raw materials are widely available; cost is relatively low; popularization is convenient; catalyst using amount is low; reaction yield is high; reaction conditions are mild; pure water is taken as the solvent; reaction is carried out at room temperature; operation is simple and convenient; application range is wide; the method is suitable for silicone additive reaction of alpha, beta- unsaturated carbonyl compounds of different types; one-pot method is adopted; and production efficiency is high.

Magnesium-induced regiospecific C-silylation of suitably substituted enoates and dienoates

The β-aryl-β-silyl and β,β-disilyl propionates have been synthesized from cinnamates and β-silyl acrylates by a regiospecific reductive C-silylation using Mg/silyl chloride/DMF system at room temperature. These reductive C-silylation conditions have also been applied to δ-aryl substituted dienoates wherein silylation took place at the δ-position leading to the synthesis of single regioisomeric allylsilanes with very high stereoselectivity.

Rhodium(I)-catalyzed enantioselective 1,4-addition of nucleophilic silicon

A rhodium(I)-catalyzed activation of a silicon-boron linkage, that is, the transmetalation of silicon from boron to rhodium(I) by means of an RhI-OH complex, enables the conjugate transfer of nucleophilic silicon onto α,β-unsaturated acceptors. Pre- or in situ formed cationic rhodium(I)-binap complexes catalyze this novel carbon-silicon bond formation with exceptional enantiocontrol, 92 to >99% ee for cyclic carbonyl and carboxyl compounds as well as >99% ee for acyclic carboxyl compounds.

Catalytic asymmetric C-Si bond formation to acyclic α,β- unsaturated acceptors by RhI-catalyzed conjugate silyl transfer using a Si-B linkage

(Chemical Equation Presented) A perfect match: The RhI-catalyzed conjugate silylation of acyclic Z-configured α,β-unsaturated carboxyl compounds including imides with silylboronic ester yields almost enantiopure α-chiral quaternary silanes (see scheme; R=aryl and (branched) alkyl, cod=cycloocta-1,5-diene, pin=pinacolato).

Chiral silanes via asymmetric hydrosilylation with catalytic CuH

CuH-catalyzed asymmetric conjugate reduction of β-silyl-α, β-unsaturated esters has been developed. Using PMHS as a stoichiometric source of hydride and in situ generated CuH ligated by Solvias' JOSIPHOS analogue PPF-P(t-Bu)2 leads to highly enantioselective 1,4-reductions.

Copper-free and copper-promoted conjugate addition reactions of bis(triorganosilyl) zincs and tris(triorganosilyl) zincates

In the course of our investigations directed towards an asymmetric copper-catalyzed silyl transfer from bis(triorganosilyl) zincs onto α,β-unsaturated carbonyl compounds, the presence of Lewis acidic lithium cations and the uncatalyzed background reaction

Copper-catalyzed conjugate addition of a bis(triorganosilyl) zinc and a methyl(triorganosilyl) magnesium

A practical copper-catalyzed conjugate silylation of α,β- unsaturated carbonyl compounds 4 utilizing bis(triorganosilyl) zinc reagent 3 is described. Moreover, mixed methyl(triorganosilyl) magnesium 7 also transfers its silyl ligand to simple enones 4 und

A study on the influence of a silicon group on the Curtius reaction

The effect of a dimethyl(phenyl)silyl group at different positions with respect to an acyl azide moiety on the Curtius reaction has been investigated. A silyl group at the β-position enhanced the reaction rate by about three times compared to a non-silylated analog. However, a silyl group at the γ-position had only a minor influence on the reaction. A diacyl azide having a silyl group at the β-position with respect to one acyl azide group and at the γ-position with respect to the other acyl azide group has been prepared and subjected to the Curtius reaction in order to evaluate the possible synthetic potential which originates from the control exerted by the silicon group in such systems.