67278-27-7

Basic information

• Product Name: Quinoline, 6,7-dimethoxy-
• CAS NO: 67278-27-7
• Molecular Formula: C11H11NO2
• Mol File: 67278-27-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Quinoline, 6,7-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 6,7-dimethoxy-(67278-27-7)
• EPA Substance Registry System: Quinoline, 6,7-dimethoxy-(67278-27-7)

Safety Data

• Hazardous Substances Data: 67278-27-7(Hazardous Substances Data)

Usage

General Description

Quinoline, 6,7-dimethoxy- is a chemical compound with the molecular formula C11H11NO2. It is a derivative of quinoline, a heterocyclic aromatic compound. The presence of two methoxy groups on the 6 and 7 positions of the quinoline ring gives this compound unique chemical properties. It is commonly used in the synthesis of pharmaceuticals, agrochemicals, and dyes. Additionally, quinoline, 6,7-dimethoxy- has been studied for its potential as an antimalarial and anticancer agent. Its chemical structure and reactivity make it a valuable building block in organic synthesis and its applications are further being explored in various fields of chemical and medicinal research.

Upstream product

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Downstream Products

• 99986-04-6 1,2,3,4-tetrahydro-6,7-dimethoxyquinoline 

Relevant articles and documents

Hypervalent iodine(III) induced intramolecular cyclization of substituted phenol ethers bearing an alkyl azido sidechain-a novel synthesis of quinone imine ketals

A novel and efficient synthesis of quinone imine ketals from substituted phenol ethers bearing an alkyl azido sidechain using a hypervalent iodine(III) reagent, phenyliodine(III) bis(trifluoroacetate) (PIFA), is described.

Straightforward synthesis of 2-propylquinolines under multicomponent conditions in fluorinated alcohols

The synthesis of 2-propylquinolines, a family of antileishmanial agents, is reported. Among the pathways explored, the 3-component Povarov reaction between butyraldehyde, aromatic amines and ethyl vinyl ether in trifluoroethanol (TFE), followed by an oxidation, offers a convenient entry to 2-propylquinolines with various substituents on positions 5-8.

A practical route to quinolines from anilines

A practical route to quinoline from anilines through acid-mediated cyclization of 3-(N-aryl-N-sulfonylamino)propionaldehydes has been developed. Treatment of the cyclization products, dihydroquinoline intermediates with KOH in DMSO leads to substituted quinolines.