67280-36-8Relevant academic research and scientific papers
A New Route to the Pavine (5,6,11,12-Tetrahydro-5,11-imino-13-methyl-dibenzocyclo-octene) Skeleton: Synthesis of (+/-)-Argemonine
Nomoto, Takashi,Takayama, Hiroaki
, p. 1113 - 1115 (1982)
A new route to the pavine skeleton was investigated starting from the readily accessible tetrahydro-6,12-methanodibenzazocine (1, R = H or Me); an efficient synthesis of a typical pavine alkaloid (+/-)-argemonine (6, R = OMe) from (1, R = OMe) was accomplished in 53percent overall yield.
ACID-CATALYZED DOUBLE-CYCLIZATION REACTIONS OF N,N-DIBENZYLAMINO-ACETALDEHYDE DIALKYL ACETALS AND RELATED COMPOUNDS: GENERAL SYNTHESIS OF 7,12-DIHYDRO-5H-6,12-METHANODIBENZAZOCINES AND RELATED COMPOUNDS
Suzuki, Takayoshi,Takamoto, Masayuki,Okamoto, Toshihiko,Takayama, Hiroaki
, p. 1888 - 1900 (2007/10/02)
A number of N,N-dibenzylaminoacetaldehyde dialkyl acetals (1) double-cyclized in 70percent perchloric acid or triflic acid (trifluoromethanesulfonic acid) to give good yields of 7,12-dihydro-5H-6,12-methanodibenzazocines (2) even when a powerful elec
RING TRANSFORMATION OF 1-AZADIBENZOBICYCLONONA-3,6-DIENES: NOVEL ROUTES TO DIBENZOPYRROLIZIDINE AND DIBENZOTROPANE
Nomoto, Takashi,Takayama, Hiroaki
, p. 1969 - 1972 (2007/10/02)
Base-induced reactions of N-methyl quaternary salts of 11b-methyl-7,11b-dihydro-5H-isoindoloisoindole (4), which were effectively transformed from readily available 1-azadibenzobicyclonona-3,6-dienes (1), were examined and consequently, 5,12-dimethyl-5,10-imino-10,11-dihydro-5H-dibenzocycloheptens (6) and 6,10b-dimethyl-5,6,6a,10b-tetrahydrobenzocyclobutisoquinolines (7) were obtained via Stevens rearrangement.
