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67372-69-4

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67372-69-4 Usage

Description

6,7-DeMethylene-6,7-dehydro Drospirenone, also known as Drospirenone EP Impurity D, is an intermediate compound in the synthesis of Drospirenone (D689500). It plays a crucial role in the production process of Drospirenone, a hormone used in various pharmaceutical applications.

Uses

Used in Pharmaceutical Industry:
6,7-DeMethylene-6,7-dehydro Drospirenone is used as an intermediate in the synthesis of Drospirenone for the following reasons:
1. It contributes to the production of Drospirenone, a hormone with various pharmaceutical applications, including contraception and hormone replacement therapy.
2. As an impurity, it helps in the quality control and assurance of the final product, ensuring the safety and efficacy of Drospirenone-based medications.
3. Its presence in the synthesis process allows for the optimization of the production method, potentially leading to more cost-effective and efficient manufacturing of Drospirenone.

Check Digit Verification of cas no

The CAS Registry Mumber 67372-69-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,3,7 and 2 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 67372-69:
(7*6)+(6*7)+(5*3)+(4*7)+(3*2)+(2*6)+(1*9)=154
154 % 10 = 4
So 67372-69-4 is a valid CAS Registry Number.

67372-69-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 17|A-Hydroxy-15|A,16|A-methylene-3-oxo-17|A-pregna-4,6-diene-21-carboxylic Acid |A-Lactone

1.2 Other means of identification

Product number -
Other names (15|A,16|A,17|A)-15,16-Dihydro-17-hydroxy-3-oxo-3'H-cyclopropa[15,16]pregna-4,6,15-triene-21-carboxylic Acid |A-Lactone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:67372-69-4 SDS

67372-69-4Relevant articles and documents

Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides

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Page/Page column 5, (2010/11/30)

A process for the epoxidation of 17-oxo-15,16-methylene steroids, in particular of drospirenone precursors, comprising the use of sulfoxonium ylides, in particular of dimethylsulfoxonium methyl ylide. The process allows to prepare in good yields 17-spiro epoxides, which can be easily transformed into 17-spironolacto-steroids.

A PROCESS FOR THE PREPARATION OF 17-HYDROXY-6β,7β;15β,l6β-BISMETHYLENE-17α-PREGN-4-ENE-3-ONE-21-CARBOXYLIC ACID γ-LACTONE AND KEY-INTERMEDIATES FOR THIS PROCESS

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Page/Page column 24-25, (2010/11/08)

The invention relates to a process for the preparation of 17-hydroxy-6β,7β;15β,16β- bismethylene-17α-pregn-4-ene-3-one-21-carboxylic acid γ-lactone of formula (I) as well as to key- intermediates for this process.

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