67398-11-2

Usage

Chemical Properties

white powder

InChI:InChI=1/C6H14NO3P/c7-6(11(8,9)10)4-2-1-3-5-6/h1-5,7H2,(H2,8,9,10)

Upstream product

• 60324-04-1 1-Aminocyclohexanphosphonsaeure-di-i-propylester 
• 56372-35-1 diethyl 1-aminocyclohexylphosphonate 
• 60-35-5 acetamide 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 17159-79-4 ethyl 4-oxocyclohexane-1-carboxylate 
• 186187-33-7 (1-Azido-cyclohexyl)-phosphonic acid diisopropyl ester 
• 186187-32-6 diethyl α-azido cyclohexylphosphonate 
• 108-94-1 cyclohexanone 
• 60324-05-2 (1-amino-cyclohexyl)-phosphonic acid diethyl ester; picrate 
• 7351-26-0 O,O-diisopropyl cyclohexylphosphonate 
• 7413-09-4 Cyclohexyl-phosphonic acid diethyl ester 

Downstream Products

• 34006-70-7 2,6-dibromocyclohexanone 
• 22554-30-9 cyclohexylideneamine 
• 108-94-1 cyclohexanone 

Relevant academic research and scientific papers

Amidoalkylation of phosphorus trichloride with acetamide and functionalized cyclic ketones-evidence of dominating role of side-reactions

The course of the reaction between phosphorus trichloride, acetamide and ethyl oxoalkanecarboxylates was studied in terms of the production of side-products. When ethyl 2-oxocycloalkane-and 4-oxocyclohexanecarboxylates were used as substrates, not only mi

Molecular amino-phosphonate cobalt-lanthanide clusters

The use of 1-amino-1-cyclohexyl phosphonic acid, a functionalised phosphonate, leads to the synthesis of two new structural types for 3d-4f phosphonate cages with unusual structural cores and which show high magnetocaloric effects.

Amidoalkylation of phosphorus trichloride with acetamide and alkyl oxocycloalkanecarboxylates

The course of the reaction between phosphorus trichloride, acetamide, and ethyl oxoalkanecarboxylates was studied in terms of the production of side-products. When alkyl 2-oxocycloalkanecarboxylates were used as substrates, together with the expected prod

A new and efficient synthesis of α-amino cycloalkylphosphonic acids via electrophilic azidation of cycloalkylphosphonates

α-Amino cyclobutyl-, cyclopentyl- and cyclohexylphosphonic acids (13) were efficiently prepared from the related unsubstituted cycloalkylphosphonates (5), in three steps including electrophilic azidation of the corresponding lithiated carbanions, catalyti

The Synthesis of 1-Aminoalkylphosphonic Acids. A Revised Mechanism of the Reaction of Phosphorus Trichloride, Amides and Aldehydes or Ketones in Acetic Acid (Oleksyszyn Reaction)

The mechanism of the amidoalkylation of trivalent phosphorus compounds in acetic acid has been reinvestigated.Evidence is presented that 1-(acylamino)alkyl acetates 5 and not N,N'-alkylidenebisamides 2 are the intermediates in this reaction.Supporting literature analogies are discussed.This paper also describes a convenient procedure for the preparation of crude (acylamino)alkyl alkanoates 5, which are excellent amidoalkylating agents.The usefulness of these reagents is demonstrated by a simple two-step "one pot" synthesis of 1-aminoalkylphosphinic acids 1.