674298-03-4

Upstream product

• 108-30-5 succinic acid anhydride 
• 674297-98-4 N¹,N⁹-bis-1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl-norspermidine 
• 94142-97-9 2-(1-hydroxyethylidene)-5,5-dimethylcyclohexane-1,3-dione 
• 56-18-8 bis(3-aminopropyl)amine 

Relevant academic research and scientific papers

Cationic lipids

The invention provides a cationic lipid comprising: (i) one head group, comprising one or more amino acids, in which at least one amino acid has a side chain that comprises a cationic moiety or a cationic precursor;(ii) a linking moiety of formula (5): [i

Solid-phase synthesis of arginine-based double-tailed cationic lipopeptides: Potent nucleic acid carriers

Herein we report a highly-efficient solid-phase strategy for the modular synthesis of 63 double-tailed lipid-peptide conjugates and their application in DNA delivery.

Solid-Phase Synthesis of 89 Polyamine-Based Cationic Lipids for DNA Delivery to Mammalian Cells

The ability of non-viral gene delivery systems to overcome extracellular and intracellular barriers is a critical issue for future clinical applications of gene therapy. In recent years much effort has been focused on the development of a variety of DNA c