67434-65-5

Basic information

• Product Name: Pyrimidine, 4-chloro-5,6-dimethyl- (7CI,9CI)
• Synonyms: 4-CHLORO-5,6-DIMETHYLPYRIMIDINE;4-chloro-5,6-dimethylpyrimidine(SALTDATA: FREE);Pyrimidine, 4-chloro-5,6-dimethyl- (7CI,9CI)
• CAS NO: 67434-65-5
• Molecular Formula: C₆H₇ClN₂
• Molecular Weight: 142.58618
• Product Categories: PYRIMIDINE
• Mol File: 67434-65-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 215-216 °C
• Boiling Point: 80-82 °C(Press: 10 Torr)
• Appearance: /
• Density: 1.184±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.12±0.26(Predicted)
• CAS DataBase Reference: Pyrimidine, 4-chloro-5,6-dimethyl- (7CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrimidine, 4-chloro-5,6-dimethyl- (7CI,9CI)(67434-65-5)
• EPA Substance Registry System: Pyrimidine, 4-chloro-5,6-dimethyl- (7CI,9CI)(67434-65-5)

Safety Data

• Hazardous Substances Data: 67434-65-5(Hazardous Substances Data)

Usage

General Description

Pyrimidine, 4-chloro-5,6-dimethyl- (7CI,9CI) is a chemical compound with the molecular formula C6H6ClN2. It belongs to the pyrimidine family and is characterized by a 4-chloro substitution at the 4th position and two methyl groups at the 5th and 6th positions of the pyrimidine ring. This chemical is used in various pharmaceutical and research applications, including as a building block for the synthesis of organic compounds and pharmaceutical drugs. Its properties and structure make it a valuable tool in medicinal chemistry and drug discovery. Additionally, it is also used as a precursor in the manufacturing of specialized chemicals and materials.

Upstream product

• 34916-78-4 4-Hydroxy-5,6-dimethyl-pyrimidin 
• 4316-97-6 4,6-dichloro-5-methylpyrimidine 
• 13061-96-6 dihydroxy-methyl-borane 
• 28456-54-4 5,6-dimethyl-2-thiouracil 
• 2302-39-8 4,5-dimethylimidazole 
• 67-66-3 chloroform 
• 34916-78-4 5,6-dimethyl-3H-pyrimidin-4-one 
• 609-14-3 2-acetylpropanoic acid ethyl ester 

Downstream Products

• 85073-88-7 (5,6-dimethyl-pyrimidin-4-yl)-phenyl-amine 
• 54568-12-6 4-Amino-5,6-dimethyl-pyrimidin 
• 85073-91-2 4-(4-Chloroanilino)-5,6-dimethylpyrimidine 
• 85074-13-1 4-(4-Isopropylanilino)-5,6-dimethylpyrimidine 

Relevant articles and documents

IMIDAZO [1, 2-C] PYRIMIDIN-2-YLMETHYLPIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS

This invention relates to imidazo[1,2-c]pyrimidin-2-ylmethyl substituted piperidine derivatives and their use as pharmaceuticals.

Reactions of Halogenomethanes in the Vapor Phase. Part 4. The Reactions of Imidazoles with Chloroform at 550 deg C, and a Comparison with their Liquid-phase Reactions with Trichloroacetate Ion or Hexachloroacetone and Base

1-Unsubstituted imidazoles and chloroform at 550 deg C in a flow system give mainly 5-chloropyrimidines, together with 4-chloropyrimidines and chloropyrazines.The effects of methyl substituents on the ratio of products is considered.The liquid-phase reactions of 2-methyl- and 2,4,5-trimethyl-imidazole under conditions in which dichlorocarbene is said to be formed in basic or neutral conditions were studied, and compared with the gas-phase reactions with chloroform.