67472-84-8Relevant academic research and scientific papers
Pd-Catalyzed Synthesis of γ-Keto Esters as Key Intermediates for the Synthesis of γ-Hydroxybutenolides
Schacht, Mathias,Mohammadi, Djawid,Schützenmeister, Nina
, p. 2587 - 2591 (2019/02/19)
We herein report a robust and safe palladium catalyzed domino-carbonylation/Suzuki–Miyaura cross-coupling reaction of vinyltosylates with arylboronic acids using Mo(CO)6 as CO-source. The derived γ-keto ester were subsequently cyclized under acidic conditions to obtain γ-hydroxybutenolides, an important structural motif, which occurs in biologically active natural products.
Nitrone cycloadditions to 1,2-diphenylcyclopropenes and subsequent transformations of the isoxazolidine cycloadducts
Diev, Vyacheslav V.,Stetsenko, Oksana N.,Tung, Tran Q.,Kopf, Juergen,Kostikov, Rafael R.,Molchanov, Alexander P.
, p. 2396 - 2399 (2008/09/18)
(Chemical Equation Presented) 1,3-Dipolar cycloaddition of C-aryl,N-aryl (or N-methyl) nitrones with a number of 1,2-diphenylcyclopropenes substituted at the C3 position occurs with the formation of expected "normal" cycloadducts (with N-methylnitrones) and products of their subsequent transformations. Among them are corresponding α-acetophenyl aziridines and tetra (or penta) -arylpyrroles. Aziridines and the normal cycloadducts can be also thermally converted to such arylpyrroles with moderate to good yields. Substitution at the C3 position of cyclopropenes by an electron acceptor group decreases the reactivity of cyclopropenes.
