126522-56-3

Upstream product

• 104-94-9 4-methoxy-aniline 
• 98-86-2 acetophenone 
• 6749-54-8 1-phenylethyl p-toluenesulfonate 
• 99-09-2 3-nitro-aniline 
• 2743-00-2 4-methoxy-N-(1-phenylethylidene)aniline 
• 1149-23-1 diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 536-74-3 phenylacetylene 
• 917-54-4 methyllithium 
• 783-08-4 [4-(benzylideneamino)phenyl]methanol 
• 2743-00-2 (E)-4-methoxy-N-(1-phenylethylidene)benzenamine 
• 98-85-1 1-Phenylethanol 
• 67-63-0 isopropyl alcohol 
• 1749-19-5 phenyl(1-phenylethylidene)amine 
• 766-82-5 1-ethynyl-3-methyl-benzene 

Downstream Products

• 2743-01-3 (R)-N-(4-methoxyphenyl)-(1-phenylethyl)amine 
• 2743-00-2 4-methoxy-N-(1-phenylethylidene)aniline 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 126522-49-4 (R)-3-Ethyl-5-methoxy-3-methyl-1-((S)-1-phenyl-ethyl)-1,3-dihydro-indol-2-one 
• 126522-49-4 (S)-3-Ethyl-5-methoxy-3-methyl-1-((S)-1-phenyl-ethyl)-1,3-dihydro-indol-2-one 
• 126522-59-6 (S)-5-Methoxy-3-methyl-1-((S)-1-phenyl-ethyl)-1,3-dihydro-indol-2-one 
• 126522-59-6 (R)-5-Methoxy-3-methyl-1-((S)-1-phenyl-ethyl)-1,3-dihydro-indol-2-one 
• 126522-65-4 (E)-2-Methyl-but-2-enoic acid (2-bromo-4-methoxy-phenyl)-((R)-1-phenyl-ethyl)-amide 
• 126522-58-5 N-(2-Bromo-4-methoxy-phenyl)-N-((R)-1-phenyl-ethyl)-acrylamide 
• 156092-13-6 (S)-4-methoxy-N-(1-phenylethyl)aniline 
• 1435647-11-2 N-(4-methoxyphenyl)-N-(1-phenylethyl)-N-benzylamine 
• 42882-26-8 N-methyl-N-(1-phenylethyl)amine 
• 880256-17-7 2-{[(4-methoxy-phenyl)-(1-phenyl-ethyl)-carbamoyl]-methylene}-malonic acid diethyl ester 
• 618-36-0 rac-methylbenzylamine 

Relevant academic research and scientific papers

A powerful Bronsted acid catalyst for the organocatalytic asymmetric transfer hydrogenation of imines

(Chemical Equation Presented) A little goes a long way: A 1 mol % loading of the chiral phosphoric acid catalyst 2 converts aromatic and aliphatic imines such as 1 into the corresponding amines (4) in high yields and enantioselectivities if treated with Hantzsch dihydropyridine 3.

Remarkable Differences in Reactivity between Benzothiazoline and Hantzsch Ester as a Hydrogen Donor in Chiral Phosphoric Acid Catalyzed Asymmetric Reductive Amination of Ketones

Described herein are differences in behavior between a Hantzsch ester and a benzothiazoline as hydrogen donors in the chiral phosphoric acid catalyzed asymmetric reductive amination of ketones with p-anisidine. The asymmetric reductive amination of ketone

C2-Symmetric Bicyclic Bisborane Catalysts: Kinetic or Thermodynamic Products of a Reversible Hydroboration of Dienes

We prepared a new class of chiral C2-symmetric bicyclic bisborane catalysts by addition reactions of internal dienes with the Piers borane, HB(C6F5)2, and an analogue, HB(p-C6F4H)2. The dependence of the addition pattern on the reaction temperature allowed us to selectively prepare two diastereomeric catalysts from a single diene precursor. The bisboranes prepared in situ exhibited excellent activity (turnover numbers up to 200 at ?40 °C) and enantioselectivity (up to 95 % ee) in imine hydrogenation reactions.

Synthesis and application of a new pseudo C2-symmetric tertiary diamine for the enantioselective addition of MeLi to aromatic imines

A new tertiary pseudo C2-symmetric diamine derived from (1S,2S)-(+)-pseudoephedrine was synthesized and tested in the enantioselective addition of methyllithium on different aromatic imines. A comparative study with a similar C2-symm

Nucleophilic addition of organomagnesiums to aldimines: Scandium triflate (Sc(OTf)3) as an effective catalyst

The 1,2-addition of organomagnesium reagents to p-methoxyphenyl (PMP)amine-derived aldimines proceeded effectively in the presence of catalytic amounts of Sc(OTf)3.

Enantioselective reaction of an imine with methyllithium catalyzed by a chiral ligand

Enantioselective reaction of benzaldehyde 4-anisidineimine 1 with methyllithium in toluene was mediated by a series of chiral aminoethers 3-11 to give the corresponding amine 2 in good to moderate ee. The chiral tridentate aminoethens 7-11 are superior to

Highly enantioselective reductive amination of simple aryl ketones catalyzed by Ir-f-Binaphane in the presence of titanium(IV) isopropoxide and iodine

Using an Ir-f-Binaphane complex as the catalyst, complete conversions and high enantioselectivies (up to 96% ee) were achieved in the asymmetric reductive amination of aryl ketones in the presence of Ti(OiPr)4 and I2. A simple and efficient method of synthesizing chiral primary amines has been realized.

Synthesis of Chiral Cleft C,N-Palladium and Iridium Complexes from 2,3:6,7-Dibenzobicyclo[3.3.1]nona-2,6-diene-4,8-dione and Their Synthetic Applications

A transition-metal-mediated functionalization of 2,3:6,7-dibenzobicyclo[3.3.1]nona-2,6-diene-4,8-dione is reported. By the use of the corresponding imine, iridium or palladium complexes were prepared, and they were well characterized by NMR and single-cry

Asymmetric hydrogenation of imines with chiral alkene-derived boron Lewis acids

With the aim of developing easily accessible chiral Lewis acids for asymmetric hydrogenation, a variety of binaphthyl-based chiral alkenes were prepared in one step from the corresponding diols. Using the in situ generated chiral boron Lewis acids through

A new pseudo C2-symmetric tertiary diamine for the enantioselective addition of MeLi to aromatic imines

A new tertiary pseudo C2-symmetric 1,2-diamine derived from (1S,2S)-(+)-pseudoephedrine was synthesized and tested in the enantioselective addition of MeLi to aromatic imines. A comparative study with the analogous C2-symmetric ligan