67519-22-6

Basic information

• Product Name: [2-(Hydroxymethyl)phenyl]acetonitrile
• Synonyms: [2-(Hydroxymethyl)phenyl]acetonitrile
• CAS NO: 67519-22-6
• Molecular Formula: C₉H₉NO
• Molecular Weight: 147.17
• Mol File: 67519-22-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 308.6±22.0 °C(Predicted)
• Appearance: /
• Density: 1.136±0.06 g/cm3(Predicted)
• PKA: 14.18±0.10(Predicted)
• CAS DataBase Reference: [2-(Hydroxymethyl)phenyl]acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(Hydroxymethyl)phenyl]acetonitrile(67519-22-6)
• EPA Substance Registry System: [2-(Hydroxymethyl)phenyl]acetonitrile(67519-22-6)

Safety Data

• Hazardous Substances Data: 67519-22-6(Hazardous Substances Data)

Upstream product

• 5597-04-6 2-cyanomethylbenzoic acid methyl ester 
• 6627-91-4 2-cyanomethylbenzoic acid 
• 98590-71-7 α-chloro-α'-cyano-o-xylene 
• 87-41-2 2-benzofuran-1(3H)-one 
• 63321-79-9 o-(N,N-dimethylaminomethyl)benzyl alcohol 
• 103-83-3 N,N'-dimethylbenzylamine 
• 151-50-8 potassium cyanide 
• 142066-41-9 2-(chloromethyl)-phenyl methanol 

Downstream Products

• 188255-00-7 [2-(1H-Tetrazol-5-ylmethyl)-phenyl]-methanol 
• 952568-66-0 2-(cyanomethyl)benzyl methyl carbonate 
• 98988-20-6 N-<2-(4-benzyloxy-3-methoxyphenyl)-ethyl>-(2-hydroxymethyl)phenylacetamide 
• 98988-21-7 N-<2-(3-benzyloxy-4-methoxyphenyl)-ethyl>-(2-hydroxymethyl)phenylacetamide 
• 98988-23-9 (+/-)-O-benzylisobharatamine 
• 98988-24-0 (S)-2-Benzyloxy-3-methoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline 
• 4385-35-7 isochroman-3-one 
• 188255-05-2 2-{4-[2-(2-Trityl-2H-tetrazol-5-ylmethyl)-benzyloxy]-phenoxymethyl}-quinoline 
• 188255-07-4 2-(4-{2-[1-(Tetrahydro-pyran-2-yl)-1H-tetrazol-5-ylmethyl]-benzyloxy}-phenoxymethyl)-quinoline 
• 188255-06-3 2-(4-{2-[2-(Tetrahydro-pyran-2-yl)-2H-tetrazol-5-ylmethyl]-benzyloxy}-phenoxymethyl)-quinoline 
• 188255-03-0 5-(2-Bromomethyl-benzyl)-2-trityl-2H-tetrazole 
• 188255-01-8 [2-(2-Trityl-2H-tetrazol-5-ylmethyl)-phenyl]-methanol 
• 188255-08-5 5-(2-Bromomethyl-benzyl)-1-(tetrahydro-pyran-2-yl)-1H-tetrazole 
• 188255-04-1 5-(2-Bromomethyl-benzyl)-2-(tetrahydro-pyran-2-yl)-2H-tetrazole 

Relevant articles and documents

RENIN INHIBITORS

Compounds, pharmaceutical compositions, kits and methods are provided for use with Renin that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.

A convergent synthesis of an LTD4 antagonist, RG12525

An efficient, convergent synthesis of an LTD4 antagonist, RG12525 (1) has been achieved through the alkylation of the (2-quinolinylmethoxy)phenol (2) with either a triphenylmethyl protected tetrazole synthon (4a) or with a tetrahydropyranyl derivative (4b). Preparation of synthons 4a and 4b, as well as novel preparation of 2 is described.

SELECTIVE REDUCTION OF THIOL ESTERS WITH SODIUM BOROHYDRIDE

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