67567-46-8

Basic information

• Product Name: 2-(BROMOMETHYL)-4-METHOXY-1-NITROBENZENE
• Synonyms: 2-(BROMOMETHYL)-4-METHOXY-1-NITROBENZENE
• CAS NO: 67567-46-8
• Molecular Formula: C₈H₈BrNO₃
• Molecular Weight: 246.06
• Mol File: 67567-46-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(BROMOMETHYL)-4-METHOXY-1-NITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(BROMOMETHYL)-4-METHOXY-1-NITROBENZENE(67567-46-8)
• EPA Substance Registry System: 2-(BROMOMETHYL)-4-METHOXY-1-NITROBENZENE(67567-46-8)

Safety Data

• Hazardous Substances Data: 67567-46-8(Hazardous Substances Data)

Usage

General Description

2-(Bromomethyl)-4-methoxy-1-nitrobenzene is a chemical compound with the molecular formula C8H8BrNO3. It is a yellow solid with a molecular weight of 246.06 g/mol. 2-(BROMOMETHYL)-4-METHOXY-1-NITROBENZENE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in the production of organic compounds. 2-(Bromomethyl)-4-methoxy-1-nitrobenzene is considered to be a hazardous substance and should be handled with care due to its potential toxicity and health hazards.

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Relevant articles and documents

Synthesis of Aryl-Substituted 3,3a,4,5-Tetrahydropyrrolo[1,2- A [ quinolin-1(2 H)-ones and 2,3,4,4a,5,6-Hexahydro-1 H-pyrido[1,2- A [quinolin-1-ones

A new route to the title benzo-fused angular tricyclic amides 3,3a,4,5-tetrahydropyrrolo- A nd 2,3,4,4a,5,6-hexahydro-1 H-pyrido[1,2- A [quinolin-1-ones is reported from 1-(tert-butyl) 6-ethyl 3-oxohexanedioate and 1-(tert-butyl) 7-ethyl 3-oxoheptanedioate. Alkylation of these β-keto diesters with a series of 2-nitrobenzyl bromides followed by acid hydrolysis and decarboxylation gives ethyl 6-(2-nitrophenyl)-4-oxohexanoates and ethyl 7-(2-nitrophenyl)-5-oxoheptanoates, respectively. Reductive amination under hydrogenation conditions followed by ester hydrolysis and condensative ring closure affords the final lactam products. The reactions proceed cleanly and only two chromatographic purifications are required.

Sensors, and methods of making and using the same

The present invention is directed, in part, to sensors for detecting metal ions, and methods of making and using the same.