675848-79-0

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 675848-78-9 C₂₅H₂₂N₆O₆ 
• 98-88-4 benzoyl chloride 
• 695197-15-0 Benzoic acid (1R,3R,4R,7S)-3-(2-amino-6-azido-purin-9-yl)-7-benzyloxy-2,5-dioxa-bicyclo[2.2.1]hept-1-ylmethyl ester 
• 675848-76-7 (1S,3R,4R,7S)-3-(2-amino-6-azidopurin-9-yl)-7-benzyloxy-1-hydroxymethyl-2,5-dioxabicyclo[2.2.1]heptane 
• 675848-77-8 (1S,3R,4R,7S)-3-(2,6-diaminopurin-9-yl)-7-hydroxy-1-hydroxymethyl-2,5-dioxabicyclo[2.2.1]heptane 
• 405290-35-9 9-(2-O-acetyl-3-O-benzyl-4C-methanesulfonyloxymethyl-5-O-methanesulfonyl-β-D-erythro-pentofuranosyl)-2-amino-6-chloropurine 
• 695197-14-9 (1R,3R,4R,7S)-3-(2-amino-6-chloropurin-9-yl)-7-benzyloxy-1-benzoyloxymethyl-2,5-dioxabicyclo[2.2.1]heptane 
• 675848-74-5 (1S,3R,4R,7S)-3-(2-amino-6-chloropurin-9-yl)-7-benzyloxy-1-methanesulfonyloxymethyl-2,5-dioxabicyclo[2.2.1]heptane 
• 293751-03-8 1,2-di-O-acetyl-3-O-benzyl-4-C-methanesulfonyloxymethyl-5-O-methanesulfonyl-D-erythro-pentofuranose 
• 10310-21-1 2-Amino-6-chloropurin 

Relevant academic research and scientific papers

Syntheses and base-pairing properties of locked nucleic acid nucleotides containing hypoxanthine, 2,6-diaminopurine, and 2-aminopurine nucleobases

Second generation 2′-O,4′-C-methylene-linked nucleotides 1-3 containing hypoxanthine, 2,6-diaminopurine, and 2-aminopurine nucleobases were synthesized and incorporated into locked nucleic acid (LNA) oligonucleotides by means of the automated phosphoramid

LNA guanine and 2,6-diaminopurine. Synthesis, characterization and hybridization properties of LNA 2,6-diaminopurine containing oligonucleotides

LNA guanine and 2,6-diaminopurine (D) phosphoramidites have been synthesized as building blocks for antisense oligonucleotides (ON). The effects of incorporating LNA D into ON were investigated. As expected, LNA D containing ON showed increased affinity t