676127-79-0Relevant articles and documents
β-amino amides from β-lactams: Application to the formal synthesis of a peptide-deformylase inhibitor
Jiang, Xinglong,Prasad, Kapa,Prashad, Mahavir,Slade, Joel,Repi?, Oljan,Blacklock, Thomas J.
, p. 3179 - 3181 (2008/02/13)
A facile and a practical synthesis of peptide-deformylase inhibitor 1 is described using an acid-catalyzed aminolysis of β-lactam 12 with pyrrolidine 6 as the key transformation. In addition, simplified conditions for the conversion of a β-hydroxy acid to
PROCESS FOR PREPARING INTERMEDIATES
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Page 21, (2008/06/13)
The present invention is directed to a process for preparing intermediates that are useful to prepare certain antibacterial N-formyl hydroxylamine compounds which are peptide deformylase inhibitors. The process makes use α β-lactam intermediate. Certain o