67618-38-6Relevant academic research and scientific papers
SYNTHESIS AND SOME REACTIONS OF 4-CARBOXY-2-THIAZOLYLHYDRAZONES
Bredikhina, Z. A.,Buzykin, B. I.,Kitaev, Yu. P.
, p. 427 - 433 (2007/10/02)
The condensation of thiosemicarbazones with bromopyruvic acid gives thiazolylhydrazone hydrobromides, which were converted to the free bases.The question of the site of protonation was studied by PMR spectroscopy.The possibility of self-protonation in 4-carboxythiazolylhydrazone crystals is not excluded.The thiazolylhydrazones are brominated in the 5 position.Both cyclization to thiazolyltriazoles and the Chetteueya-Walker reaction are realized in the case of oxidation with lead tetraacetate.
SYNTHESIS OF 2-HYDRAZONO-4-ETHOXYCARBONYLTHIAZOLES
Usol'tseva, S. V.,Andronnikova, G. P.,Nikolaeva, S. L.
, p. 2172 - 2176 (2007/10/02)
Various methods of synthesis of hydrazones derived 2-hydrazino-4-ethoxycarbonylthiazole are discussed and a series of such hydrazones have been prepared.The preferred method for the synthesis of hydrazones of aromatic and heterocyclic aldehydes is the one-step cyclization reaction of thiosemicarbazide, ethyl bromopyruvate, and a carbonyl compound, and for the synthesis of aliphatic hydrazones - the trans-hydrazonization reaction of 2-isopropylidenehydrazino-4-ethoxycarbonylthiazole by the action of carbonyl compounds.
SYNTHESIS AND TRANSFORMATIONS OF 2-AMINO-1,3,4-THIADIAZINES
Usol'tseva, S. V.,Andronnikova, G. P.,Nikolaeva, S. L.,Lebedev, A. T.,Shevyrin, V. A.
, p. 442 - 446 (2007/10/02)
Depending on the reaction conditions, 2-amino-1,3,4-thiadiazine and 2-hydrazinothiazole derivatives were obtained by cyclization of thiosemicarbazide with ethyl bromopyruvate in concentrated hydrochloric acid.The rearrangements of 5-carbonyl-substituted 2
