676458-03-0

Basic information

• Product Name: N⁶-benzoyl-3',5'-di-O-tert-butyldimethylsilyl-4'-C-ethynyl-2'-deoxyadenosine
• CAS NO: 676458-03-0
• Molecular Weight: 607.9
• Mol File: 676458-03-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N⁶-benzoyl-3',5'-di-O-tert-butyldimethylsilyl-4'-C-ethynyl-2'-deoxyadenosine(CAS DataBase Reference)
• NIST Chemistry Reference: N⁶-benzoyl-3',5'-di-O-tert-butyldimethylsilyl-4'-C-ethynyl-2'-deoxyadenosine(676458-03-0)
• EPA Substance Registry System: N⁶-benzoyl-3',5'-di-O-tert-butyldimethylsilyl-4'-C-ethynyl-2'-deoxyadenosine(676458-03-0)

Safety Data

• Hazardous Substances Data: 676458-03-0(Hazardous Substances Data)

Upstream product

• 167700-45-0 5'-aldehyde-2'-deoxy-6-N-benzoyl-3'-O-tertbutyldimethylsilyl adenosine 
• 64325-78-6 N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine 
• 51549-40-7 6-N-benzoyl-3'-O-(tert-butyldimethylsilyl)-2'-deoxyadenosine 
• 146578-12-3 5’-O-(4,4’dimethoxytrityl)-N6-(benzoyl)-3’-O-tert-butyldimethylsilyldeoxyadenosine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 583047-58-9 N-{9-[5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-5-hydroxymethyl-tetrahydro-furan-2-yl]-9H-purin-6-yl}-benzamide 
• 583047-59-0 N⁶-benzoyl-3',5'-di-O-tert-butyldimethylsilyl-4'-C-cyano-2'-deoxyadenosine 
• 583047-57-8 N⁶-benzoyl-3'-O-tert-butyldimethylsilyl-2'-deoxy-4'-C-hydroxymethyladenosine 

Relevant articles and documents

Design, efficient synthesis, and anti-HIV activity of 4′-C-cyano- and 4′-C-ethynyl-2′-deoxy purine nucleosides

Some 4′-C-ethynyl-2′-deoxy purine nucleosides showed the most potent anti-HIV activity among the series of 4′-C-substituted 2′-deoxynucleosides whose 4′-C-substituents were methyl, ethyl, ethynyl and so on. Our hypothesis is that the smaller the substitue