676566-79-3

Upstream product

• 100-39-0 benzyl bromide 
• 676566-78-2 (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (1R,4S,5R)-4-(methoxymethoxy)-3-oxo-2-azabicyclo[2.2.2]oct-7-ene-5-carboxylate 
• 676566-77-1 (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (1R,4S,5R)-4-(methoxymethoxy)-2-[(4-methylphenyl)sulfonyl]-3-oxo-2-azabicyclo[2.2.2]oct-7-ene-5-carboxylate 

Downstream Products

• 676566-80-6 (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (1R,2R,6R,7R,10S)-8-benzyl-1-(methoxymethoxy)-4,4-dimethyl-9-oxo-3,5-dioxa-8-azatricyclo[5.2.2.0^2,6]undecane-10-carboxylate 
• 660849-28-5 (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (1R,4R,5S,7R,8R)-2-benzyl-7,8-dihydroxy-4-(methoxymethoxy)-3-oxo-2-azabicyclo[2.2.2]octane-5-carboxylate 
• 660849-26-3 (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (1R,4S,5S)-2-benzyl-4-(methoxymethoxy)-3-oxo-2-azabicyclo[2.2.2]oct-7-ene-5-carboxylate 

Relevant academic research and scientific papers

Synthesis and Evaluation as Glycosidase Inhibitors of Isoquinuclidines Mimicking a Distorted β-Mannopyranoside

Racemic and enantiomerically pure manno-configured isoquinuclidines were synthesized and tested as glycosidase inhibitors. The racemic key isoquinuclidine intermediate was prepared in high yield by a cycloaddition (tandem Michael addition/aldolisation) of