676596-99-9

Upstream product

• 162269-90-1 3-bromo-4-(methoxymethoxy)benzaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 2973-78-6 3-bromo-4-hydroxybenzylaldehyde 
• 34841-06-0 3-bromo-4-methoxybenzylaldehyde 
• 676596-98-8 4-methoxymethoxy-3-vinyl-benzaldehyde 

Downstream Products

• 1044871-09-1 2-(4-hydroxy-3-(2-hydroxyethyl)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one 
• 1044872-54-9 2-[3-(2-hydroxy-ethyl)-4-methoxymethoxy-phenyl]-5,7-dimethoxy-3H-quinazolin-4-one 
• 676596-89-7 C₃₄H₅₇FO₃Si₃ 
• 676596-90-0 tert-butyl-[4-[2-(3,5-dimethoxy-phenyl)-vinyl]-2-(2-fluoro-ethyl)-phenoxy]-dimethyl-silane 
• 676597-01-6 toluene-4-sulfonic acid 2-(5-formyl-2-methoxymethoxy-phenyl)-ethyl ester 
• 676597-02-7 4-(tert-butyl-dimethyl-silanyloxy)-3-(2-fluoro-ethyl)-benzaldehyde 
• 676597-59-4 3-(2-fluoro-ethyl)-4-methoxymethoxy-benzaldehyde 
• 676597-00-5 3-(2-hydroxy-ethyl)-4-methoxymethoxy-benzaldehyde 

Relevant academic research and scientific papers

TREATMENT OF DISEASES BY EPIGENETIC REGULATION

The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of cancer, including NUT midline carcinoma, Burkitt's Lymphoma, Acute Myelogenous Leukemia, and Multiple Myeloma; autoimmune or inflammatory diseases or conditions, and sepsis.

COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES

The present disclosure relates to compounds, which are useful for regulating the expression of apolipoprotein A-I (ApoA-I), and their use for treatment and prevention of cardiovascular disease and related disease states, including cholesterol- or lipid-related disorders, such as, for example, atherosclerosis.

Syntheses and radical scavenging activities of resveratrol derivatives

Nine new resveratrol derivatives, having bromo, iodo, and fluoroethyl groups, were designed and synthesized. All compounds having free phenol groups showed good free radical scavenging activity. Among them, 2-bromoresveratrol 19 has a similar free radical scavenging activity to (+)-catechin.