67686-03-7 Usage
General Description
1-BENZYL-4-(CHLOROMETHYL)PIPERIDINE HYDROCHLORIDE is a chemical compound that belongs to the class of piperidine derivatives. It is commonly used as an intermediate in the synthesis of pharmaceutical drugs, particularly in the production of antipsychotic and anxiolytic medications. 1-BENZYL-4-(CHLOROMETHYL)PIPERIDINE HYDROCHLORIDE is a white to off-white solid that is soluble in water and ethanol. It is also known for its potential use in the treatment of mood disorders and other central nervous system-related conditions. Additionally, 1-BENZYL-4-(CHLOROMETHYL)PIPERIDINE HYDROCHLORIDE is a potent inhibitor of the serotonin 5-HT2 and dopamine D2 receptors, making it a valuable tool in neuroscience research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 67686-03-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,6,8 and 6 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 67686-03:
(7*6)+(6*7)+(5*6)+(4*8)+(3*6)+(2*0)+(1*3)=167
167 % 10 = 7
So 67686-03-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H18ClN/c14-10-12-6-8-15(9-7-12)11-13-4-2-1-3-5-13/h1-5,12H,6-11H2
67686-03-7Relevant articles and documents
1-Benzyl-4-chloromethylpiperidine: A building block in the synthesis of compounds of pharmacological interest
Rodríguez-Franco, María Isabel,Fernández-Bachiller, María Isabel
, p. 911 - 915 (2002)
The first synthesis of 1-benzyl-4-(chloromethyl)piperidine (1) is described, together with its application in the synthesis of potential pharmaceuticals. Reaction of 1 with several purines in basic medium proceed through the initial formation of 1-benzyl-1-azoniabicyclo[2.2.1]heptane system, which then undergoes nucleophilic attack at two different carbons, yielding N-benzylpiperidine and N-benzylpyrrolidine derivatives.
