67686-03-7 Usage
Uses
Used in Pharmaceutical Industry:
1-BENZYL-4-(CHLOROMETHYL)PIPERIDINE HYDROCHLORIDE is used as a key intermediate in the synthesis of various pharmaceutical drugs, specifically for the production of antipsychotic and anxiolytic medications. Its chemical structure allows for the development of compounds that can effectively target and modulate the activity of specific receptors in the central nervous system, contributing to the management of psychiatric and mood disorders.
Used in Neuroscience Research:
In the field of neuroscience, 1-BENZYL-4-(CHLOROMETHYL)PIPERIDINE HYDROCHLORIDE is utilized as a potent inhibitor of serotonin 5-HT2 and dopamine D2 receptors. This makes it a valuable tool for studying the roles of these receptors in various physiological and pathological processes, as well as for the development of new therapeutic agents targeting these receptors.
Used in Drug Development:
1-BENZYL-4-(CHLOROMETHYL)PIPERIDINE HYDROCHLORIDE's ability to inhibit specific receptors makes 1-BENZYL-4-(CHLOROMETHYL)PIPERIDINE HYDROCHLORIDE a crucial component in drug development. It aids in the creation of new medications designed to treat a range of central nervous system-related conditions, including mood disorders, by providing a foundation for the design of more effective and targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 67686-03-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,6,8 and 6 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 67686-03:
(7*6)+(6*7)+(5*6)+(4*8)+(3*6)+(2*0)+(1*3)=167
167 % 10 = 7
So 67686-03-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H18ClN/c14-10-12-6-8-15(9-7-12)11-13-4-2-1-3-5-13/h1-5,12H,6-11H2
67686-03-7Relevant academic research and scientific papers
Rodríguez-Franco, María Isabel,Fernández-Bachiller, María Isabel
, p. 911 - 915 (2002)
The first synthesis of 1-benzyl-4-(chloromethyl)piperidine (1) is described, together with its application in the synthesis of potential pharmaceuticals. Reaction of 1 with several purines in basic medium proceed through the initial formation of 1-benzyl-1-azoniabicyclo[2.2.1]heptane system, which then undergoes nucleophilic attack at two different carbons, yielding N-benzylpiperidine and N-benzylpyrrolidine derivatives.
