677027-04-2

Basic information

• Product Name: Benzenemethanamine, N-(2-iodophenyl)-N-methyl-
• CAS NO: 677027-04-2
• Molecular Formula: C14H14IN
• Molecular Weight: 323.176
• Mol File: 677027-04-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-(2-iodophenyl)-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-(2-iodophenyl)-N-methyl-(677027-04-2)
• EPA Substance Registry System: Benzenemethanamine, N-(2-iodophenyl)-N-methyl-(677027-04-2)

Safety Data

• Hazardous Substances Data: 677027-04-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 15111-14-5 2-iodo-N-(phenylmethylene)-benzenamine 
• 615-43-0 2-iodophenylamine 
• 50-00-0 formaldehyd 
• 76464-99-8 N-benzyl-2-iodoaniline 

Downstream Products

• 677027-15-5 trans-[Pd(C₆H₄N(Me)CH₂Ph-2)I(PPh₃)2] 
• 677027-13-3 [Pd(κ2-C6H4N(Me)CH2Ph-2)I(PPh3)] 
• 81235-65-6 3-benzyl-1-methyl-2-phenyl-1H-indole 
• 1443647-01-5 4,9-dimethyl-2-tosyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole 
• 1443646-78-3 4-(iodomethyl)-9-methyl-2-tosyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole 
• 1443647-16-2 N-allyl-N-(3-(2-(benzyl(methyl)amino)phenyl)prop-2-ynyl)-4-methylbenzenesulfonamide 
• 1757-72-8 1-methyl-2-phenyl-1H-indole-3-carbaldehyde 
• 1153648-32-8 1-methyl-3-pentyl-2-phenyl-1H-indole 
• 3558-28-9 1,3-dimethyl-2-phenyl-1H-indole 

Relevant articles and documents

A new synthesis of indoles via intramolecular cyclization of ?-alkynyl N,N-dialkylanilines promoted by KOt-Bu/DMSO

2-Aryl indoles could be prepared in excellent yields via the intramolecular cyclization of ?-alkynyl N,N-dialkylanilines. The reaction is efficiently promoted by the catalytic amount of KOt-Bu in DMSO at room temperature. A reaction mechanism involving α-

An efficient approach to 1,2,3-trisubstituted indole via rhodium catalyzed carbene Csp3-H bond insertion

A method for convenient synthesis of N-alkyl-2-aryl-indole-3-carbaldehyde has been described. A variety of highly valuable indolyl aldehydes have been prepared through this method. Electron donating groups on both aromatic rings (anilinyl and benzyl) facilitate the formation of the desired products. A benzylic C-H insertion by rhodium carbene is the key step for this transformation. This journal is

Potassium tert-butoxide promoted intramolecular arylation via a radical pathway

Potassium tert-butoxide mediated intramolecular cyclization of aryl ethers, amines, and amides was efficiently performed under microwave irradiation to provide the corresponding products in high regioisomeric ratios. The reaction proceeds via single-electron transfer to initiate the formation of an aryl radical, followed by a kinetically favored 5-exo-trig and subsequent ring expansion.