81235-65-6

Upstream product

• 52604-16-7 3-(Phenylmethyl)-2-phenylindole 
• 77-78-1 dimethyl sulfate 
• 1083-30-3 dihydrochalcone 
• 618-40-6 1-Methyl-1-phenylhydrazine 
• 15111-14-5 2-iodo-N-(phenylmethylene)-benzenamine 
• 76464-99-8 N-benzyl-2-iodoaniline 
• 1422274-11-0 N-benzyl-N-methyl-2-(phenylethynyl)aniline 
• 677027-04-2 N-benzyl-2-iodo-N-methylaniline 
• 100-52-7 benzaldehyde 
• 21771-91-5 phenyl phenetyl ketone phenylhydrazone 

Downstream Products

• 53603-63-7 1-methyl-2-phenyl-3-nitroso-1H-indole 
• 81235-52-1 2-benzyl-1,2-dihydro-1-methyl-2-phenyl-3H-indol-3-one 
• 90995-71-4 3-Benzyl-1-methyl-5-nitro-2-phenyl-1H-indole 
• 90995-75-8 1-methyl-2-phenyl-3-(4-nitrobenzyl)indole 
• 90995-76-9 1-methyl-2-phenyl-3-(4-nitrobenzyl)-5-nitroindole 

Relevant academic research and scientific papers

A new synthesis of indoles via intramolecular cyclization of ?-alkynyl N,N-dialkylanilines promoted by KOt-Bu/DMSO

2-Aryl indoles could be prepared in excellent yields via the intramolecular cyclization of ?-alkynyl N,N-dialkylanilines. The reaction is efficiently promoted by the catalytic amount of KOt-Bu in DMSO at room temperature. A reaction mechanism involving α-

A new synthesis of indoles via intramolecular cyclization of ο-alkynyl N,N-dialkylanilines promoted by KOt-Bu/DMSO

2-Aryl indoles could be prepared in excellent yields via the intramolecular cyclization of ο-alkynyl N,N-dialkylanilines. The reaction is efficiently promoted by the catalytic amount of KOt-Bu in DMSO at room temperature. A reaction mechanism involving α-

Reactions of Dimethyl Acetylenedicarboxylate with Indoles having Bulky 3-Substituents, and Further Reactions of Pyrroloindoles

The addition of dimethyl acetylenedicarboxylate to nine pyrroloindoles, and to nine N-methylindoles with bulky 3-substituents, has yielded twenty three new adducts.Their structures, elucidated mainly from spectroscopy which includes extensive diagnostic use of 13C-1H n.m.r. coupling constants, show several novel features, but all adducts are related to known adduct types.The results show that for relatively unstrained pyrroloindoles, the formation of an amino-ketone intermediate is still significant, but not dominant, that bulky 3-alkyl substituents of indoles can be eliminated to give 2-hydroxycarbazoles, and also that 3-phenyl groups appear to inhibit any reaction.

Addition of Dimethyl Acetylenedicarboxylate to 1,2,3-Trisubstituted Indoles having no Hydrogen on the Carbon Atom attached to C-2.

Addition of dimethyl acetylenedicarboxylate to seven 1,2,3-trisubstituted indoles having no hydrogen on the carbon atom attached to C-2, has yielded fourteen adducts which are mainly fused γ-lactones, but which include a new phenanthridine-dione, a novel spiro-dihydroindole, and a carbazole formed by the loss of methane.All structures were elucidated by spectroscopy.