6774-40-9Relevant academic research and scientific papers
Copper-Catalyzed Acyloxycyanation of Alkynes with Acetonitrile: Regioselective Construction of Cyclic Acrylonitriles by 6-endo or 5-exo Cyclization
Zhu, Yamin,Shen, Zengming
supporting information, p. 3515 - 3519 (2017/09/13)
An efficient difunctionalization of alkynes by tandem iodolactonization and copper-catalyzed cyanation using acetonitrile as a cyanating reagent is reported for the first time. This approach can afford cyano-containing isocoumarin or phthalide derivatives
One-pot synthesis of 2,3-substituted benzo[b]thiophenes via Cu(i) catalysed intramolecular cyclisation from dithioesters
Sandhya, Nagarakere. C.,Nandeesh, Kebbahalli. N.,Rangappa, Kanchugarakoppal S.,Ananda, Sannaiah.
, p. 29939 - 29946 (2015/05/13)
Efficient synthesis of benzo[b]thiophenes from o-halophenyl acetonitrile has been achieved. This novel one-pot procedure involves CuI and pivalic acid catalyzed C-S bond formation using dithioesters followed by a heterocyclization reaction. This efficient
Synthesis of benz[c]benzothiopheno[2,3-e]azepines via Heck-type coupling and Pictet-Spengler reaction
David, Emilie,Rangheard, Claudine,Pellet-Rostaing, Stéphane,Lemaire, Marc
, p. 2016 - 2020 (2008/02/05)
New benz[c]benzothiopheno[2,3-e]azepine derivatives 1 of potential biological properties were synthesised in four steps from bromobenzo[b] thiophene. The synthetic pathway is based on 'Heck-type' and Pictet-Spengler reactions. Georg Thieme Verlag Stuttgar
Synthesis of new 2-arylbenzo[b]thiophenes using 'Heck-type' technology
Fournier Dit Chabert, Jérémie,Gozzi, Christel,Lemaire, Marc
, p. 1829 - 1833 (2007/10/03)
Direct 3-substituted benzothiophene arylation using a Heck-type reaction with Pd(OAc)2/n-Bu4NBr as a catalytic system is reported. This reaction was found to perform relatively fast whatever the electron-donating or the electron-withdrawing group at position 3. We also extended this reaction to several aromatic halides, such as benzene, naphthalene and pyridine derivatives, synthesising new 2-arylbenzo[b]thiophenes in moderate to good yields.
