67797-33-5

Upstream product

• 78175-62-9 3-Hydroxy-2-isopropyl-N,N-dimethyl-3-phenyl-thiobutyramide 
• 67-64-1 acetone 

Downstream Products

• 95680-00-5 3-Hydroxy-2-isopropyl-5-phenyl-pentanethioic acid dimethylamide 
• 95680-00-5 3-Hydroxy-2-isopropyl-5-phenyl-pentanethioic acid dimethylamide 
• 78175-54-9 2-(Hydroxy-phenyl-methyl)-3,N,N-trimethyl-thiobutyramide 
• 78175-54-9 2-(Hydroxy-phenyl-methyl)-3,N,N-trimethyl-thiobutyramide 
• 90421-14-0 3,N,N-Trimethyl-2-(phenyl-trimethylsilanyloxy-methyl)-thiobutyramide 
• 90421-14-0 3,N,N-Trimethyl-2-(phenyl-trimethylsilanyloxy-methyl)-thiobutyramide 
• 90421-18-4 (1S,2S)-2-Dimethylaminomethyl-3-methyl-1-phenyl-butan-1-ol 
• 78175-67-4 2-(Hydroxy-diphenyl-methyl)-3,N,N-trimethyl-thiobutyramide 
• 78175-54-9 (S)-2-((R)-Hydroxy-phenyl-methyl)-3,N,N-trimethyl-thiobutyramide 
• 344442-83-7 2-(Hydroxy-phenyl-methyl)-3,N,N-trimethyl-thiobutyramide 

Relevant academic research and scientific papers

SUR LES ORGANOMETALLIQUES ISSUS DE THIOAMIDES. I. REACTIVITE AVEC LES ALDEHYDES ET CETONES; STEREOCHIMIE DE LA CONDENSATION AVEC LA t-BUTYL-4 CYCLOHEXANONE ET LE BENZALDEHYDE

Organometallic compounds derived from thioamides RCH2CSN(R3)2 condense normally with aldehydes and saturated ketones.Condensation with 4-t-butylcyclohexanone leads predominantly to equatorial attack by the organometallic compound.These results suggest that the organometallic structure is RCH=C(SM)N(R3)2.The stereoselectivity of the reaction with benzaldehyde depends on R and R3; a mechanism for the formation of β-hydroxythioamides is discussed.