67820-94-4

Basic information

• Product Name: Pyridazine, 6-chloro-3,4-bis(4-methoxyphenyl)-
• CAS NO: 67820-94-4
• Molecular Formula: C18H15ClN2O2
• Molecular Weight: 326.782
• Mol File: 67820-94-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pyridazine, 6-chloro-3,4-bis(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridazine, 6-chloro-3,4-bis(4-methoxyphenyl)-(67820-94-4)
• EPA Substance Registry System: Pyridazine, 6-chloro-3,4-bis(4-methoxyphenyl)-(67820-94-4)

Safety Data

• Hazardous Substances Data: 67820-94-4(Hazardous Substances Data)

Upstream product

• 433330-77-9 5,6-bis-(4-methoxy-phenyl)-4,5-dihydro-2H-pyridazin-3-one 
• 93098-08-9 ethyl 3-(4-methoxybenzoyl)-3-(4-methoxyphenyl)propionate 
• 67295-41-4 3,4-bis-(4-methoxy-phenyl)-4-oxo-butyric acid 
• 120-44-5 1,4-di(4-methoxyphenyl)ethanone 
• 70768-92-2 5,6-bis(4-methoxyphenyl)-2H-pyridazin-3-one 

Downstream Products

• 67820-93-3 N'-[5,6-bis-(4-methoxy-phenyl)-pyridazin-3-yl]-hydrazinecarboxylic acid ethyl ester 
• 388606-70-0 6-allyl-3,4-bis(4-methoxyphenyl)pyridazine 

Relevant articles and documents

Mono- and di-substituted 5,6-diphenyl-3-alkylaminopyridazines active as ACAT inhibitors

A series of mono- or di-para-substituted 5,6-diphenyl-3-alkylaminopyridazines were synthesized and their inhibitory activity against acyl-CoA:cholesterol acyltransferase (ACAT) was tested on the enzyme prepared from rat liver microsomes. The compound which combines a chlorine atom on the 6-phenyl ring and a n-hexylamino chain showed a significant enhancement of activity with respect to the unsubstituted derivative. Attempts to correlate the activity of the compounds to their structural features, also through theoretical calculations, are reported.