6784-25-4

Basic information

• Product Name: diformyl dapsone
• Synonyms: diformyl dapsone;Bis[p-(formylamino)phenyl] sulfone;DFD;Formilone;N,N'-(Sulfonyldi-1,4-phenylene)bisformamide;WR455000;WR-6798
• CAS NO: 6784-25-4
• Molecular Formula: C₁₄H₁₂N₂O₄S
• Molecular Weight: 304.34
• Mol File: 6784-25-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.3704 (rough estimate)
• Refractive Index: 1.6930 (estimate)
• CAS DataBase Reference: diformyl dapsone(CAS DataBase Reference)
• NIST Chemistry Reference: diformyl dapsone(6784-25-4)
• EPA Substance Registry System: diformyl dapsone(6784-25-4)

Safety Data

• Hazardous Substances Data: 6784-25-4(Hazardous Substances Data)

Usage

Uses

Diformyldapsone is an effective treatment of murine and human P. carinii pneumonitis. Also, it is a derivative of the parent compound, Dapsone (D193250), which is an antibacterial used in the treatment of dermatitis herpetiformis.

Upstream product

• 64-18-6 formic acid 
• 80-08-0 dapsone 
• 80-07-9 4,4'-dichlorodiphenyl sulphone 

Downstream Products

• 3117-85-9 C₁₄H₈N₂O₂S 
• 1620164-65-9 octaethyl sulfonyldiphenyl-4,4`-bis[aminomethylidene(bisphosphonate)] 
• 1620164-72-8 sulfonyldiphenyl-4,4`-bis[aminomethylidene(bisphosphonic)] acid 

Relevant articles and documents

Acidic ionic liquid immobilized on nanoporous Na+-montmorillonite as an efficient and reusable catalyst for the formylation of amines and alcohols

In this work, nanoporous sodium montmorillonite clay (Na+-MMT) was used as a support for the immobilization of 1-methyl-3-(trimethoxysilylpropyl)-imidazolium hydrogen sulfate. The Na+-MMT chemical modification ([Na+-MMT-[pmim]HSO4) was confirmed by a variety of techniques including Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy and potentiometric titration. The catalytic performance of this immobilized acidic ionic liquid was probed for the N-formylation of a variety of amines using formic acid under solvent-free conditions. This reagent is also useful for the formylation of benzylic alcohols. The procedure gave the products in excellent yields in very short reaction times. Also, this catalyst can be reused ten times without loss of its catalytic activity.