67996-22-9Relevant articles and documents
N-Heterocyclic Carbene-Catalyzed β-Indolylation of α-Bromoenals with Indoles
Sun, Shaofa,Lang, Ming,Wang, Jian
supporting information, p. 5704 - 5708 (2019/12/24)
An unprecedented example of NHC-catalyzed β-indolylation of α-bromoenals with indoles has been developed. This concise protocol features several advantages (mild reaction conditions, broad substrate scope) and constructs synthetically useful building blocks, namely β-biaryl methylene esters. Notably, the β-biaryl methylene-type fragment is widely found in natural products or pharmaceuticals. (Figure presented.).
Catalytic enantioselective alkylation of heteroaromatic compounds using alkylidene malonates
Zhuang,Hansen,Jorgensen
, p. 347 - 348 (2007/10/03)
A catalytic enantioselective alkylation of heteroaromatic compounds using alkylidene malonates has been developed; the reaction proceeds for different heteroaromatic compounds with alkylidene malonates in high yield and enantiomeric excess.