2309-38-8

Basic information

• Product Name: furosta-5,20(22)-dien-3,26-diyl diacetate
• Synonyms: Nsc224266
• CAS NO: 2309-38-8
• Molecular Formula: C₃₁H₄₆O₅
• Molecular Weight: 498.6939
• Mol File: 2309-38-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 574.4°C at 760 mmHg
• Flash Point: 239.8°C
• Density: 1.12g/cm³
• Vapor Pressure: 3.37E-13mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: furosta-5,20(22)-dien-3,26-diyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: furosta-5,20(22)-dien-3,26-diyl diacetate(2309-38-8)
• EPA Substance Registry System: furosta-5,20(22)-dien-3,26-diyl diacetate(2309-38-8)

Safety Data

• Hazardous Substances Data: 2309-38-8(Hazardous Substances Data)

Upstream product

• 75-36-5 acetyl chloride 
• 512-04-9 diosgenin 
• 123748-70-9 (22R,25R)-3β,16β,22,26-tetra-acetoxy-cholest-5-ene 
• 108-24-7 acetic anhydride 

Downstream Products

• 1061-54-7 diosgenin acetate 
• 1162-53-4 16-dehydropregnenolone 
• 512-04-9 diosgenin 
• 6808-14-6 pseudodiosgenin 
• 145-13-1 Pregnenolone 
• 1913-47-9 3β,20α-diacetoxypregn-5-ene 
• 901-57-5 pregn-5-ene-3β,20α-diol 
• 566-56-3 5α-pregnan-3β,20α-diol 
• 145-14-2 (20S)-20-hydroxypregn-4-en-3-one 
• 57-83-0 Progesterone 
• 93176-77-3 3,26-dimethoxy-23-(p-dimethylaminobenzylidenyl)-furost-5,20-diene 
• 979-02-2 16-dehydropregnenolone acetate 

Relevant articles and documents

Continuous Flow Synthesis of 16-Dehydropregnenolone Acetate, a Key Synthon for Natural Steroids and Drugs

A telescoped multistep process to provide the continuous delivery of 16-dehydropregnenolone acetate (16-DPA) from diosgenin is described. The method was evaluated through batch screenings that helped to identify critical bottlenecks and flowability, and the best conditions were optimized in flow systems before the individual steps were telescoped together into a single integrated flow process. Further highlights of our approach include the use of efficient in-line extraction operations and reaction monitoring, the avoidance of time-consuming purifications between steps, and improvement of efficiency and safety standards.