6815-55-0

Basic information

• Product Name: Pyrrolidine, 1-(cyclohexylidenemethyl)-
• CAS NO: 6815-55-0
• Molecular Formula: C11H19N
• Molecular Weight: 165.279
• Mol File: 6815-55-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Pyrrolidine, 1-(cyclohexylidenemethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolidine, 1-(cyclohexylidenemethyl)-(6815-55-0)
• EPA Substance Registry System: Pyrrolidine, 1-(cyclohexylidenemethyl)-(6815-55-0)

Safety Data

• Hazardous Substances Data: 6815-55-0(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 108-94-1 cyclohexanone 
• 27491-70-9 dimethyl diazomethylphosphonate 
• 68571-10-8 cyclohexyl(pyrrolidin-1-yl)methanone 
• 2043-61-0 cyclohexanecarbaldehyde 

Downstream Products

• 25363-24-0 (pyrrolidinyl-1)methyl-1 cyclohexanol 
• 1192-37-6 methylenecyclohexane 
• 30834-42-5 spiro[5.5]undec-1-en-3-one 
• 1890-25-1 spiro[5.5]undecan-3-one 
• 1007559-75-2 C₂₅H₃₅N₃S 
• 1007559-76-3 C₂₆H₃₀ClN₃OS 
• 712-50-5 Cyclohexyl phenyl ketone 
• 2789-44-8 cyclohexyl(p-tolyl)methanone 
• 7469-80-9 cyclohexyl 4-methoxyphenyl ketone 
• 3277-80-3 (4-chlorophenyl)(cyclohexyl)methanone 
• 419543-02-5 cyclohexyl-(4-trifluoromethylphenyl)-methanone 
• 898792-14-8 4-(cyclohexanecarbonyl)benzonitrile 
• 898769-06-7 (3-bromophenyl)(cyclohexyl)methanone 
• 10404-26-9 cyclohexyl(naphthalen-2-yl)methanone 

Relevant articles and documents

Cross-Coupling of Secondary Amides with Tertiary Amides: The Use of Tertiary Amides as Surrogates of Alkyl Carbanions for Ketone Synthesis

In recent years, exciting progress has been made in the field of direct transformation of amides, nevertheless, the condensation between two amides remains rare and restricted to homo-coupling reactions. Herein, we report the cross-coupling of secondary amides with tertiary amides, which provides a synthesis of ketones under mild conditions, and features the use of tertiary amides as surrogates of alkyl carbanions. The method relies on the coupling of enamines, generated from tertiary amides by catalytic partial reduction of tertiary amides with Vaska's catalyst, with nitrilium ions, formed in situ from secondary amides via activation with trifluoromethanesulfonic anhydride, and on the subsequent deformylation.

N-SUBSTITUTED PHENYLACETAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

A compound represented by the formula: (I) wherein R1 represents a methoxy group, a hydroxyl group or a hydrogen atom; R2 represents a hydrogen atom, a C1-4 alkyl group, a C1-4 alkylcarbonyl group or an arylcarbonyl group; and D represents a group represented by the formula (A), (B) or (C) below. (A) (B) (C) This compound is useful as a therapeutic agent for a pain or inflammation induced by any one of various morbid conditions such as neuropathic pain, rheumatoid arthritis and osteoarthritis.

Scope and Pathway of Catalytic Aminomethylation of Olefins

We describe a general and high-yield one-step process for synthesis of tertiary and secondary amines from olefins, carbon monoxide, water, and a nitrogen source in the presence of transition-metal compounds as catalysts.We find this chemistry, initially d