68185-01-3

Upstream product

• 21911-68-2 ethyl 2-(p-tolylamino)acetate 
• 143-37-3 acetamidine 
• 177750-08-2 1-(4-methylphenyl)ethenylacetamide 
• 177750-10-6 N-(1-(4-methoxy)phenylethyl)acetamide 
• 218903-49-2 N-(1-([1,1'-biphenyl]-4-yl)vinyl)acetamide 
• 177750-13-9 N-(1-(4-fluorophenyl)vinyl)acetamide 
• 208118-80-3 1-(4-chlorophenyl)ethenylacetamide 
• 177750-12-8 N-{1-(4-bromophenyl)vinyl}acetamide 
• 1373120-00-3 N-(1-(4-iodophenyl)vinyl)acetamide 
• 177750-24-2 N-(1-(naphthalen-2-yl)vinyl)acetamide 
• 1202033-32-6 N-[1-(thiophen-3-yl)vinyl]acetamide 
• 57957-24-1 N-(1-phenylvinyl)acetamide 
• 60-35-5 acetamide 
• 106-49-0 p-toluidine 

Relevant academic research and scientific papers

Copper catalysis: One-pot simultaneous synthesis of quinolines and gem-diamine derivatives

A copper(II)-catalyzed oxidative reaction for the one-pot simultaneous synthesis of quinolines and gem-diamine derivatives from N-arylglycine ethyl esters and enamides is described. In this reaction, the two fragments in an enamide substrate react with th

Copper-Catalyzed Cross-Dehydrogenative-Coupling Reaction of N -Arylglycine Esters with Imides or Amides for Synthesis of α-Substituted α-Amino Acid Esters

A simple and highly efficient cross-dehydrogenative-coupling (CDC) reaction between N -aryl glycine esters and imides or amides by the catalysis of a copper salt without the requirement of peroxide agents is described. The novel reaction provides a facile approach for the synthesis of α-substituted α-amino acid esters through C-H/N-H oxidative cross-coupling. A possible mechanism for the CDC reaction by using copper as a catalyst and air as the terminal oxidant is also proposed. This synthetic approach has the advantages of good yields, simple operation and mild reaction conditions.