68277-06-5Relevant academic research and scientific papers
Study of a new ‘chiral proton’ organocatalyst with hydrolase activity: application in azlactone racemic dynamic resolution
Fuentes de Arriba, ángel L.,Rubio, Omayra H.,Simón, Luis,Alcázar, Victoria,Monleón, Laura M.,Sanz, Francisca,Morán, Joaquin R.
, p. 819 - 823 (2017/06/13)
For the first time, a 1,3-ketoenol system is described as an acid catalyst with hydrolytic activity. The combination of an enol and a pyridine/benzimidazole supported on a benzofuran skeleton allowed the creation of a novel bifunctional organocatalyst, wh
Transition metal complexes as linkers for solid phase synthesis: Chromium carbonyl complexes as linkers for arenes
Comely,Gibson,Hales,Peplow
, p. 2526 - 2531 (2007/10/03)
Substrates containing aromatic rings have been attached to 'polymer supported triphenylphosphine' using a chromium carbonyl linker, chemically manipulated, and released from the polymer to demonstrate the potential use π-bound ligands in linker chemistry. Immobilisation of the phenylalanine derivative Fmoc-Phe-OtBu via its aromatic ring has been achieved and the resulting resin successfully subjected to standard amino acid deprotection and coupling procedures.
Vinyl carboxylate an acylating reagent for selective acylation of amines and diols
Chen,Chen,Chen,Wang
, p. 3583 - 3584 (2007/10/02)
Vinyl group of vinyl alkylate (C=2 or 16) and vinyl benzoate have been found to be a good leaving group in acylation of alcohols (40-50% yield) and amines (in 60-90% yield).
Some Studies on Peptide Analogues Involving the Sulphinamide Group
Merricks, David,Sammes, Peter G.,Walker, Edward R. H.,Henrick, Kim,McPartlin, Mary M.
, p. 2169 - 2176 (2007/10/02)
The title compounds are of interest as possible transition state inhibitors of peptidases.A route to N-(alkylsulphinyl)amino acids is described.A method for generating α-benzamidosulphinamides is reported; a general route to such systems failed owing to t
