68305-82-8Relevant articles and documents
Development of a Direct Photocatalytic C-H Fluorination for the Preparative Synthesis of Odanacatib
Halperin, Shira D.,Kwon, Daniel,Holmes, Michael,Regalado, Erik L.,Campeau, Louis-Charles,Dirocco, Daniel A.,Britton, Robert
, p. 5200 - 5203 (2015)
Late-stage C-H fluorination is an appealing reaction for medicinal chemistry. However, the application of this strategy to process research appears less attractive due to the formation and necessary purification of mixtures of organofluorines. Here we dem
Sulfonamide formation from sodium sulfinates and amines or ammonia under metal-free conditions at ambient temperature
Yang, Kai,Ke, Miaolin,Lin, Yuanguang,Song, Qiuling
supporting information, p. 1395 - 1399 (2015/03/18)
A novel, practical and highly efficient method for the construction of a variety of sulfonamides mediated by I2 was demonstrated. The reaction proceeds readily at room temperature using a variety of sodium sulfinates and amines or ammonia in water in a metal-, base-, ligand-, or additive-free protocol. Primary, secondary and tertiary sulfonamides were obtained in good to excellent yields with a broad range of functional group tolerability. This journal is
Facile ring-opening of azabicyclic [3.1.0]-and [4.1.0]aminocyclopropanes to afford 3-piperidinone and 3-azepinone
Lee, Jisun,Berritt, Simon,Prier, Christopher K.,Joullie, Madeleine M.
supporting information; experimental part, p. 1083 - 1085 (2011/04/22)
Azabicyclic [3.1.0] and [4.1.0] Kulinkovich products underwent a facile reduction/fragmentation to afford a variety of 3-piperidinones and 3-azepinones, respectively, in the presence of catalytic palladium on carbon and formic acid in an atmosphere of hyd
Palladium catalysed queuing processes. Part 2: Termolecular cyclization-anion capture employing carbon monoxide as a relay switch with in situ generated vinylstannanes
Anwar, Usman,Casaschi, Adele,Grigg, Ronald,Sansano, José M
, p. 1361 - 1367 (2007/10/03)
The palladium catalysed termolecular queuing processes involving aryl iodides, carbon monoxide (1 atm) and in situ generated vinylstannanes as terminating agents afford a variety of complex heterocyclic α,β-unsaturated ketones in good yield.