68385-34-2

Upstream product

• 34046-70-3 2-(hydroxyamino)-2-methyl-1-phenylpropan-1-one 
• 33687-74-0 1-phenyl-2-methyl-2-nitropropanol 

Downstream Products

• 34405-42-0 α-(1-amino-1-methylethyl)benzenemethanol 
• 100-52-7 benzaldehyde 
• 127-06-0 acetone oxime 
• 145769-66-0 N-(1,1-dimethyl-2-hydroxy-2-phenylethyl)-α-3-nitrophenylnitrone 
• 69295-30-3 C₁₇H₁₉NO₂ 
• 145828-98-4 C₁₃H₁₈NO₄ 
• 145769-72-8 3-hydroxy-4,4-dimethyl-2-methoxycarbonyl-5-phenyloxazolidine 
• 259672-32-7 C₁₇H₁₉N₂O₃ 
• 259672-11-2 C₁₉H₂₂NO₄ 
• 259672-10-1 2-(4-methoxy-phenyl)-4,4-dimethyl-5-phenyl-4,5-dihydro-oxazole 3-oxide 

Relevant academic research and scientific papers

SYNTHESIS OF STABLE OXAZOLIDINE NITROXYL RADICALS WITH METHOXY GROUPS AT THE α-CARBON ATOMS TO THE RADICAL SITE

The condensation of α-hydroxyaminoalcohols with aldehydes and acetone gave 3-hydroxyoxazolidines and tautomeric N-(2-hydroxyethyl)-α-arylnitrones, whose oxidation by PbO2 in methanol leads to stable oxazolidine nitroxyl radicals with methoxy groups at Cs

Electrochemical Reduction of Tertiary Nitroalkanes to Amines

Electrochemical reduction of tertiary nitroalkanes, 2-substituted-1,1-dimethyl-1-nitroethanes (1), was investigated in aqueous buffer solutions.In polarography, 1 with a phenyl group and/or a hydroxyl group at the 2-position showed an ill-defined wave in the weakly acidic and neutral pH region at relatively high negative potentials, in addition to a well-defined wave arising from the reduction of 1 to the corresponding hydroxylamine (2).Controlled potential electrolysis of 1 at the potential of the former wave gave the 1,1-dimethylethylamines (3) as well as the hydroxylamines 2.The amines 3 are formed exclusively from 2, probably via the O-protonated form.It is suggested that a phenyl group at the 2-position facilitates the reduction of 2 to 3 by enhancing the adsorption of 2 at the mercury cathode and that a hydroxyl group, while it interferes with the adsorption, assists the reduction by intramolecular hydrogen-bonding to stabilize the O-protonated form of 2.Keywords - tertiary nitroalkane; alkylhydroxylamine; electrochemical reduction; polarography; controlled potential electrolysis.

Oxidation of Hydroxylamine Derivatives. VI. Anodic Oxidation of N-Alkyl-β-hydroxyhydroxylamines in Aqueous Buffer Solution

Anodic oxidation of N-alkylhydroxylamines with and without a β-hydroxy group was studied by cyclic voltammetry and controlled potential electrolysis in aqueous buffer solution of pH 8.8.The hydroxylamines with a β-hydroxy group were oxidized initially to the corresponding nitroxides and gave the final products via two routes; i) cleavage of the (α)C-(β)C bond to give aldehydes and oximes, and ii) disproportionation of the nitroxides to form the nitroso compounds.The hydroxylamines without a β-hydroxy group did not undergo cleavage of the (α)C-(β)C bond and gave nitroso compounds.Substituents on the α and β carbons affected the product distribution.When a phenyl group or two methyl groups were present on the (β)C, or one methyl group was present on both (α)C and (β)C, (α)C-(β)C bond cleavage was predominant. Keywords - N-alkyl-β-hydroxyhydroxylamine; anodic oxidation; C-C bond fission; C-nitroso compound; aldehyde; oxime; azoxy compound