68430-93-3

Basic information

• Product Name: (2-HYDROXY-5-METHYLPHENYL)(1-PHENYL-1H-PYRAZOL-4-YL)METHANONE
• Synonyms: TIMTEC-BB SBB001120;4-(2-HYDROXY-5-METHYLBENZOYL)-1-PHENYLPYRAZOLE;1-PHENYL-4(2-HYDROXY-5-METHYLBENZOYL)PYRAZOLE;(2-HYDROXY-5-METHYLPHENYL)(1-PHENYL-1H-PYRAZOL-4-YL)METHANONE
• CAS NO: 68430-93-3
• Molecular Formula: C₁₇H₁₄N₂O₂
• Molecular Weight: 278.31
• Mol File: 68430-93-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-HYDROXY-5-METHYLPHENYL)(1-PHENYL-1H-PYRAZOL-4-YL)METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-HYDROXY-5-METHYLPHENYL)(1-PHENYL-1H-PYRAZOL-4-YL)METHANONE(68430-93-3)
• EPA Substance Registry System: (2-HYDROXY-5-METHYLPHENYL)(1-PHENYL-1H-PYRAZOL-4-YL)METHANONE(68430-93-3)

Safety Data

• Hazardous Substances Data: 68430-93-3(Hazardous Substances Data)

Upstream product

• 42059-81-4 3-formyl-6-methylchromone 
• 100-63-0 phenylhydrazine 
• 91546-67-7 6-methyl-3-(N,N-dimethylhydrazonomethyl)chromone 
• 59-88-1 phenylhydrazine hydrochloride 
• 112635-27-5 3-[(6-methyl-4-oxo-4H-1-benzopyran-3-yl)methylene]pentan-2,4-dione 
• 72164-96-6 3-formyl-6-methylchromone oxime 
• 88021-72-1 2-(4-oxo-6-methyl-4H-1-benzopyran-3-yl)-1,3-dioxolane 

Downstream Products

• 112030-42-9 2-benzoyl-5-methyl-3-(1-phenyl-1H-pyrazol-4-yl)benzofuran 
• 93065-37-3 5-Methyl-3-(1-phenyl-1H-pyrazol-4-yl)-benzofuran-2-carboxylic acid 
• 118545-67-8 3-(4-Methoxy-phenyl)-6-methyl-4-(1-phenyl-1H-pyrazol-4-yl)-chromen-2-one 
• 118545-59-8 6-Methyl-3-phenyl-4-(1-phenyl-1H-pyrazol-4-yl)-chromen-2-one 
• 118545-63-4 3-(4-Chloro-phenyl)-6-methyl-4-(1-phenyl-1H-pyrazol-4-yl)-chromen-2-one 
• 93065-70-4 [4-Methyl-2-(1-phenyl-1H-pyrazole-4-carbonyl)-phenoxy]-acetic acid ethyl ester 

Relevant articles and documents

In vitro cytotoxicity of hydrazones, pyrazoles, pyrazolo-pyrimidines, and pyrazolo-pyridine synthesized from 6-substituted 3-formylchromones

Pyrazoles 4a-f, hydrazones 5a-c and 6a-c, pyrazolo[1,5-a]pyrimidines 7a, b, and pyrazolo[3,4-b]pyridine 8 were prepared in good yields (80-95%) from the reaction of 6-substituted (H, Me, F) 3-formylchromones 1a-c with N-substituted hydrazines 2a-c and ami

One pot synthesis of 4-(2-hydroxybenzoyl)-pyrazoles from 3- formylchromones under microwave irradiation in solvent free conditions

The synthesis of 4-(2-hydroxybenzoyl)pyrazoles (3) was achieved in a single step by the reaction of 3-formylchromones (1) with Phenylhydrazine or Tosylhydrazine under microwave irradiation without a solvent.

Benzopyrans: Part XXIX - Reactions of some simple condensates of 4-oxo-4H-1-benzopyran-3-carboxaldehyde with nitrogen nucleophiles

The chromone 2, derived from the title aldehyde 1, gives the pyrazole 8 (R3 = Ph) with phenylhydrazine whereas 5 gives with H2NNHR3 (R3 =H and Ph) the pyridine derivatives (9).Hydroxylamine converts the chromones 2-4 into pyridine-1-oxides (13-15), respectively.The reaction of 1 with ethyl glycinate in the presence of pyridine affords the pyrroles 20 and 21, the former (20) being detected in the product mixture derived from 4 and ethyl glycinate.

Heterocyclic Systems: Part XIII - Reactions of 3-N,N-Dimethylhydrazonomethyl-, Oximomethyl- and Cyano-chromones with Nucleophiles Containing Nitrogen

Reactions of the title chromones (3, 9, 10) with nitrogen containing nucleophiles (5-7) have been studied.When treated with phenylhydrazine, the hydrazone (9) produces the same pyrazole 17 (R'=Ph) as obtained by reacting chromone-3-carboxaldehyde (8) with

Hetericyclic Systems. Part 14. Condensation Reactions of 2-(4-Oxo-4H-1-benzopyran-3-yl)-1,3-dioxolane

Nitrogen nucleophiles under 1,4-addition with the title acetal (4; R=H, Me, and Cl) to give an intermediate that ultimately produces in most cases the same product as is obtained from the corresponding aldehyde (3) under similar conditions.Thus, compound