68451-84-3

Upstream product

• 613-92-3 N-hydroxyl-benzamidine 
• 74-11-3 para-chlorobenzoic acid 
• 122-01-0 4-chloro-benzoyl chloride 
• 613-92-3 N-hydroxybenzenecarboximidamide 
• 100-47-0 benzonitrile 

Downstream Products

• 28825-13-0 5-(4-chlorophenyl)-3-phenyl-1,2,4-oxadiazole 
• 613-92-3 N-hydroxyl-benzamidine 
• 74-11-3 para-chlorobenzoic acid 
• 65573-12-8 4-chloro-5H-1,2,3-dithiazole-5-one 
• 75318-44-4 4-chloro-5H-1,2,3-dithiazole-5-thione 
• 180723-56-2 5-Cyano-3-phenyl-1,2,4-thidiazole-4-oxide 
• 1126-46-1 Methyl 4-chlorobenzoate 

Relevant academic research and scientific papers

Clean one-pot synthesis of 1,2,4-oxadiazoles under solvent-free conditions using microwave irradiation and potassium fluoride as catalyst and solid support

Potassium fluoride was found to be an efficient catalyst and solid support for the synthesis of 3,5-disubstituted-1,2,4-oxadiazoles. In this work, a one-pot method for the synthesis of these compounds from the reaction of nitriles with hydroxylamine hydro

Parallel synthesis of 1,2,4-oxadiazoles from carboxylic acids using an improved, uronium-based, activation

We describe the synthesis of 1,2,4-oxadiazoles from carboxylic acids and amidoximes using 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) as an activating agent of the carboxylic acid function for the O-acylation step. This method was used for the synthesis of a library of 24 1,2,4-oxadiazoles.

SYNTHESIS AND MASS SPECTRA OF AROYLBENZAMIDOXIMES

The synthesis of several O-aroylbenzamidoximes I and of some N-aroyl (II) as well as of bis(aroyl)benzamidoximes (III) is described and their fragmentation pattern in the mass spectra is discussed.O- and N-Aroylbenzamidoximes are distinguished on the basis of their mass spectra since the O-derivatives afford the ion corresponding to the acid +. whereas the N-derivatives the ion corresponding to the amide +H>.