68510-79-2Relevant articles and documents
One-Pot Synthesis of 2,3,5-Trisubstituted Thiophenes through Three-Component Assembly of Arylacetaldehydes, Elemental Sulfur, and 1,3-Dicarbonyls
Wang, Zilong,Qu, Zhonghua,Xiao, Fuhong,Huang, Huawen,Deng, Guo-Jun
supporting information, p. 796 - 800 (2018/02/21)
The three-component reaction for the synthesis of 2-arylthiophenes has been developed. Easily available arylacetaldehydes, 1,3-dicarbonyls, and elemental sulfur were directly assembled through cascade condensation/ annulation under base conditions. The pr
Copper-Catalyzed Coupling of 2-Siloxy-1-alkenes and Diazocarbonyl Compounds: Approach to Multisubstituted Furans, Pyrroles, and Thiophenes
Tan, Wei Wen,Yoshikai, Naohiko
, p. 5566 - 5573 (2016/07/14)
We report herein copper(II)-catalyzed cyclization reactions of silyl enol ethers derived from methyl ketones with α-diazo-β-ketoesters or α-diazoketones to afford 2-siloxy-2,3-dihydrofuran derivatives or 2,3,5-trisubstituted furans, respectively, under mild conditions. The former cyclization products serve as versatile 1,4-diketone surrogates, allowing facile preparation of 2,3,5-trisubstituted furans, pyrroles, and thiophenes.
Rhodium Thiavinyl Carbenes from 1,2,3-Thiadiazoles Enable Modular Synthesis of Multisubstituted Thiophenes
Kurandina, Daria,Gevorgyan, Vladimir
supporting information, p. 1804 - 1807 (2016/05/19)
The rhodium-catalyzed transannulation reaction between 1,2,3-thiadiazoles and alkynes, proceeding via intermediacy of the previously unknown Rh thiavinyl carbene, toward a highly efficient and regioselective synthesis of up to fully substituted thiophenes is described.
INHIBITORS OF HISTONE DEACETYLASE
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Page/Page column 91; 92, (2009/06/27)
ABSTRACT OF THE DISCLOSURE This invention relates to compounds and methods for the inhibition of HDAC enzymatic activity. More particularly, the invention provides for compounds of formula (I), (I) and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, and racemic and scalemic mixtures, diastereomers and enantiomers thereof, wherein L, M, n, R, W, X and Y are as defined in the specification.
Palladium-catalyzed perarylation of 3-thiophene- and 3-furancarboxylic acids accompanied by C-H bond cleavage and decarboxylation
Nakano, Masaya,Tsurugi, Hayato,Satoh, Tetsuya,Miura, Masahiro
supporting information; experimental part, p. 1851 - 1854 (2009/04/10)
3-Thiophene- and 3-furancarboxylic acids efficiently undergo perarylation accompanied by cleavage of the three C-H bonds and decarboxylation upon treatment with excess aryl bromides in the presence of a palladium catalyst to give the corresponding tetraarylated products in good yields.
