29113-66-4Relevant articles and documents
Unusual Thermal Rearrangement of the endo-Peroxides of 2,5-Dimethylfurans
Graziano, M. Liliana,Iesce, M. Rosaria,Scarpati, Rachele
, p. 720 - 721 (1981)
Thermal rearrangement of the endo-peroxides of the 2,5-dimethylfurans (1b) and (1c) in refluxing benzene leads to the corresponding diepoxides (4b) and (4c), which provides a convenient entry to the synthesis of these compounds which are structurally rela
Transition-Metal-Free Approach to Polysubstituted Furans
You, Changming,Zhang, Zhenming,Tu, Yongliang,Tang, Hong,Wang, Yuanfeng,Long, Da,Zhao, Junfeng
, p. 3902 - 3910 (2020/03/23)
A convenient and straightforward strategy for the synthesis of 2,3-disubstituted and 2,3,5-trisubstituted furans via a base-promoted domino reaction of β-keto compounds with vinyl dichlorides is described. This transition-metal-free approach proceeds under operationally simple reaction conditions featuring easily available starting materials, a broad substrate scope, and good functional group tolerance.
Copper-Catalyzed Coupling of 2-Siloxy-1-alkenes and Diazocarbonyl Compounds: Approach to Multisubstituted Furans, Pyrroles, and Thiophenes
Tan, Wei Wen,Yoshikai, Naohiko
, p. 5566 - 5573 (2016/07/14)
We report herein copper(II)-catalyzed cyclization reactions of silyl enol ethers derived from methyl ketones with α-diazo-β-ketoesters or α-diazoketones to afford 2-siloxy-2,3-dihydrofuran derivatives or 2,3,5-trisubstituted furans, respectively, under mild conditions. The former cyclization products serve as versatile 1,4-diketone surrogates, allowing facile preparation of 2,3,5-trisubstituted furans, pyrroles, and thiophenes.
